Current vaccine strains show high neutralization against the latest variants, but the LP.8.1 antigen may provide similar or moderately higher cross-reactive antibody response.
Plaque growth can lead to a higher risk of heart attack, stroke, and other life-threatening cardiovascular events for as long as 1 year.
Post-exertional malaise, or exercise intolerance, was seen in 36% of those with long COVID.
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Delayed diagnoses of lung, breast, and colorectal cancers will likely be on the rise because of missed cancer screenings during the pandemic.
Protection against ICU admission and death was 69% 1 week to 2 months after a bivalent dose and 50% at 4 to 6 months.
Leading the list of symptoms are post-exertion malaise, fatigue, brain fog, dizziness, GI symptoms, heart palpitations, and changes in sexual desire.
In another COVID development, the FDA today announced full approval for the use of Paxlovid in adults at risk for more severe disease.
Data suggest an increased risk of new-onset mental illness only in SARS-CoV-2–positive patients aged 70 and older.
Experts from the Annenberg Public Policy Center prefer "Vaccination Safety Monitor" or "Vaccination Safety Watch" over VAERS.
Excess deaths were 22%, 22%, and 25% above baseline in low-, medium-, and high-vaccination states in the first year of the pandemic, but 23%, 22%, and 16%, respectively, in the second.
Particulate matter, nitrous oxide, and black carbon exposures were all associated with severe outcomes.
Maternal death occurred more often in patients who had cardiac arrest, acute kidney injury, or intracranial hemorrhage (brain bleed).
The 2 heart conditions occurred within a week of vaccination in under 40 cases per million doses delivered in kids 5 to 17 years old.