The United States has been in a 'protracted health crisis' for decades, the researchers say.
Plaque growth can lead to a higher risk of heart attack, stroke, and other life-threatening cardiovascular events for as long as 1 year.
Post-exertional malaise, or exercise intolerance, was seen in 36% of those with long COVID.
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The study shows that lingering symptoms could not be explained by pre-existing health conditions, but are instead linked to social disadvantages.
Though hospitalizations and other markers trended lower, the CDC received reports of 17 more pediatric flu deaths.
People who later had or long COVID had higher resting heart rates and lower daily step counts at least 3 weeks prior to SARS-CoV-2 infection.
The reminders didn't lead to differences in COVID-related clinical outcomes, however.
A total of 9% of placebo recipients contracted COVID-19 from a household member, compared with 3% of ensitrelvir recipients, for a 67% risk reduction.
22 studies featured patients who had been hospitalized for COVID-19.
Nine percent of people who described themselves as permanently sick or disabled had long COVID.
Lower risks for vaccinated participants were also seen when restricting the analyses to the pre-Omicron and Omicron periods, sex, age, or previous infection.
From 2021 to 2023, 23% of participants developed long-COVID symptoms, with 56% of those infected in 2021 reporting symptoms for 2 years.
German researchers say the answer may be in virus-reactive memory T cells, which are triggered by COVID infection.
