At least two doses of the novel oral polio vaccine type 2 are needed to interrupt transmission
Effectiveness was consistent across sexes and age-groups: 80% in females, 86% in males, 80% in children, and 83% in adults.
Gavi's expanded vaccine portfolio fits its goal of ensuring that lower-income countries have access to key vaccines as soon as possible.
Direct contact, especially providing nursing care for or sleeping in the same space as the index patient, increased the odds of infection.
Four Americas countries this year have reported cases or Oropouche virus, a disease spread by certain midges and mosquitoes.
Cases are even rising in countries such as Costa Rica and Mexico that typically see dengue rises in the second half of the year.
Viremia findings also add support for the vaccine's use as postexposure prophylaxis.
Pakistan has its second wild poliovirus type 1 case of the year, 4 countries report rising mpox, and the WHO has new resources.
Emergent has received a 10-year BARDA contract worth up to $704 million for advanced development and supply of a monoclonal antibody.
The phase 1 trial will enroll 36 healthy adults at two US clinical sites.
