Malaria, HIV, and TB programs are already feeling impacts from the cuts, with scale-backs also depleting healthcare services in Afghanistan.
Several CDC pages have been taken down amid a move by the Trump administration to remove all language related to gender identity and LGBTQ issues.
With a total of $100 billion spent, PEPFAR is the largest public health commitment in history by any country to address a single disease.
The report also spotlights the urgency of vaccines for pathogens such as group A Streptococcus and Klebsiella pneumoniae, which are increasingly resistant to antimicrobials.
During the study, 9 people tested positive for HIV, most of them during the pandemic, which the authors say is more than expected.
Researchers estimate that 85 pathogens accounted for 704 million disability-adjusted life years globally in 2019.
COVID-19 was associated with a 30% increased subsequent risk of a first cardiovascular event.
A total of 7% of residents with HIV were reinfected with SARS-CoV-2, compared with 5% of those without HIV.
Severe complications included necrotizing (flesh-eating) skin lesions, lung dysfunction sometimes accompanied by nodules, and secondary infections and sepsis.
Of 57 hospitalized patients with severe manifestations, most were Black men with AIDS.
