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Re-creating known pathogenic viruses and making existing bacteria more dangerous are among the top threats.
Some experts say that offering a manual for re-creating an orthopoxvirus is inherently dangerous.
Researchers are relieved to resume experiments, but some public health questions remain.
In a sample from a patient who died, researchers saw signs that the H7N9 virus had started to mutate to a form resistant to Tamiflu.
Though the technology isn't likely within reach of do-it-yourselfers, it could already be in use by rogue governments, experts say.
The group voted unanimously on policy regarding avian flu and other viruses.
Palmer MJ. Learning to deal with dual use. Science 2020 Mar 6;367(6482):1057
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