MCR-1

Mobilized colistin resistance gene

Recent News

Feb 17, 2022

News Scan for Feb 17, 2022

H5 avian flu at third Indiana farm
MCR-1 resistance gene in E coli
Antibiotic for plague, melioidosis
Jun 28, 2021

News Scan for Jun 28, 2021

MCR-1 colonization in China
Salmonella and shrimp
Jamestown Canyon virus in NJ
Jun 08, 2020
Chickens feeding in Guangdong, China

Study finds short-term impact of China's ban on colistin for animals

The ban on using colistin for growth promotion is tied to reduced MCR-1 in both animals and people.

Feb 13, 2020

News Scan for Feb 13, 2020

Recent DRC Ebola cases
MCR-1 resistance gene in Wyoming
Pneumococcal disease in kids
More H5N6 in Vietnam
Dec 11, 2019

Stewardship / Resistance Scan for Dec 11, 2019

Cefdinir antibiotic stewardship target
MCR colistin resistance in 2 nations
Oct 11, 2019

Stewardship / Resistance Scan for Oct 11, 2019

Probiotics and C diff risk
MCR genes on Algerian farms
Jul 25, 2019

Stewardship / Resistance Scan for Jul 25, 2019

Cost of hospital C diff
MCR-1, MCR-3 E coli combo
New resistant Pseudomonas cases
Jul 23, 2019
MRSA bacteria

Reports profile MCR gene in South America, first detection in Uruguay

Brazil, Bolivia, and Argentina had the most MCR-positive isolates, a review finds.

Jul 10, 2019

Stewardship / Resistance Scan for Jul 10, 2019

UK antibiotic prescribing decline
MCR-1 E coli in Michigan
Jun 14, 2019
Salmonella colonies in petrie dish

Colistin-resistance gene MCR-3.1 makes US appearance

The sample was from 2014, so the discovery has implications for the US spread of colistin resistance.

Resources & Literature

Recent Literature

Campos-Madueno E, Moser AI, Risch M, et al. Exploring the global spread of Klebsiella grimontii isolates possessing blaVIM-1 and mcr-9. Antimicrob Agents Chemother 2021 (published online Jun 28)

Cherak Z, Loucif L, Moussi A, et al. Epidemiology of mobile colistin resistance (mcr) genes in aquatic environments. J Glob Antimicrob Resist 2021 (published online Aug 23)

Dadashi M, Sameni F, Bostanshirin N, et al. Global prevalence and molecular epidemiology of mcr-mediated colistin resistance in Escherichia coli clinical isolates: a systematic review. J Glob Antimicrob Resist 2021 (published online Nov 14)

Fayad AA, Azzi ME, Sleiman A, et al. Acquired resistome and plasmid sequencing of mcr-1 carrying MDR Enterobacteriaceae from poultry and their relationship to STs associated with humans. JAC Antimicrob Resist 2022 Feb 7;4(1)

Jamin C, Sanders BK, Zhou M, et al. Genetic analysis of plasmid-encoded mcr-1 resistance in Enterobacteriaceae derived from poultry meat in the Netherlands. JAC Antimicrob Resist 2021 Nov 11;3(4)

Ha VTT, Tran LD, Mai NTT, et al. Potential spread of mcr-9-carrying IncHI2 plasmids in Enterobacter hormaechei in Vietnam. J Glob Antimicrob Resist 2021 (published online Nov 18)

Hamame A, Davoust B, Rolain JM, et al. Genomic characterisation of an mcr-1 and mcr-3-producing Escherichia coli strain isolated from pigs in France. J Glob Antimicrob Resist 2022 (published online Jan 24)

Kim JS, Kwon MJ, Jeon SJ, et al. Identification of a carbapenem-resistant Enterobacter kobei clinical strain co-harboring mcr-4.3 and mcr-9 in Republic of Korea. J Glob Antimicrob Resist (Letter) 2021 (published online Jun 13)

Lv Z, Shen Y Liu W, et al. Prevalence and risk factors of mcr-1-positive volunteers after colistin banning as animal growth promoter in China: a community-based case-control study. Clin Microbiol Infect 2021 (published online Jun 28)

Nakamura A, Nakamura T, Niki M, et al. Genomic characterization of ESBL- and carbapenemase-positive enterobacteriaceae co-harboring mcr-9 in Japan. Front Microbiol 2021 (published online Aug 24)

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