High-dose flu vaccine contains 4 times as much hemagglutinin as standard-dose flu vaccine.
The risk of influenza was found to be elevated in people who received the vaccine only in the previous season.
The return on investment of up to $4,637 per vaccination course translates to billions of dollars in net monetary benefits to society, the authors say.
Among the 767 adults in the study, 32% said they had no primary care provider.
A literature review found pneumococcal conjugate vaccines were associated with some protection against flu and other viral respiratory tract infections.
The Yamagata flu B lineage hasn't been confirmed since March 2020 and is no longer thought to pose a health threat.
Overall pooled VE was 39% in preventing flu-associated outpatient visits.
For the first time, the mid-season report from four VE networks covers both pediatric and adult age groups.
The group again recommended trivalent vaccine versions, given that 1 of the 2 influenza B strains hasn't been detected since 2020.
Data across 9 flu seasons reveal that flu vaccine effectiveness wanes 9% every 28 days beginning 41 days post-vaccination in adults but not in kids.
