"[Funding for a game-changing flu vaccine] is really about national security. The infectious diseases are against all of us. And this is one where we really, as a global community, need to come together and say, what is it that we need to do that is necessary to hold off, if not get the upper hand against these microbes?"
"The ultimate goal is this game-changing flu vaccine which would make seasonal flu vaccine obsolete. There is a hell of a challenge getting people vaccinated every year. We are realizing vaccine user fatigue that comes with that. We see rates of vaccine use going down, not up."
"The principles of making horsepox virus are not different [from smallpox]. Do you want to lay out a roadmap for the bad guys? The work in Canada [by Evans] is virtually a road map. Now almost every Tom, Dick, and Harry can do it."
"[The flu vaccine is] causing actually almost an erosion of confidence in vaccines as opposed to increasing confidence. … If you look at over the past five years, the number of people being vaccinated has actually leveled off or in some groups actually decreased. And that's because I think people are really confused about this vaccine and what it does."
"I don’t think we're that close at all [in developing a game-changing universal flu vaccine]. I think the kind of work that's gone on has been critical and important, but it's only the first 5 feet of what would need to be a 100-foot rope."
"Seasonal flu is bad, but this is not that unusual. When a totally new flu strain emerges in the human population, that's when we really have a problem."
"We live in a global just-in-time economy. A pandemic could put a screeching halt to that. [Aviation] is really a very accelerated way to move the virus that's unprecedented in human history."
"People have painted this as the worst flu in recent memory, and it's probably not good. Any death from influenza is an unfortunate tragedy, but at this point, I'm hard-pressed to say that this is a significantly elevated year for influenza. It's more of a media issue than an actual data issue."
"If you look at the confidence intervals, they all overlap. The results are very similar. There’s nothing here that's surprising. It's very consistent with what we've been seeing."
"You have a major funding deficit at the federal level, which is really dangerous. If we had a replay of the Spanish flu [the 1918 pandemic], we’d be hosed.”
"What's the business model here? Am I going to spend more than $1 billion to make a [universal flu] vaccine when I can only sell $20 million worth of doses?"
"We've really set ourselves up for a very, very serious situation. I'm afraid that this [relying on offshore medicine and devices] could be the worst mistake here with the flu. With the fall hurricanes we experienced, we're now seeing that very, very major problem, because over 60% of all IV bags we use in medical around the world are made in Puerto Rico."
"Putting a few million dollars here and there into a [game-changing] flu vaccine is not going to get us what we need. It's going to take billions of dollars and extensive collaboration and research to get a vaccine done."