Approximately 40% of participants did not seroconvert or achieve a conservative neutralization threshold post-vaccination.
RSV activity remains high, with pediatric hospitalizations increasing across most of the country.
52% of adults think the vaccine given to pregnant individuals to protect their infants from RSV is effective, up 10 percentage points from 42% in October of 2023.
The South and West have the highest flu levels, while COVID levels are highest in the Midwest.
The report urges citizens and healthcare workers not yet vaccinated against COVID-19 or seasonal flu to do so as soon as possible before next week's holidays.
Following Listeria outbreaks and recalls, an ongoing review identified several steps that can be quickly implemented.
Though previous trials have shown high vaccine effectiveness, most trialed adults were 75 years or older.
Flu activity continues to elevate, and COVID-19 markers are also starting to rise from very low levels.
Disease burden, hospitalization rates have stayed the same from 2017 to 2024.
The FDA says the hold is related to concerns about safety findings from a now-paused clinical trial of two RSV vaccine candidates in infants.