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The regimen was recently recommended by the WHO for treating patients with drug-resistant TB.

Though antimicrobial resistance was linked to increased mortality, patient characteristics also played a role.

The government said a key goal is controlling major human and animal pathogens and that the plan sets new targets for combatting AMR.

Infections caused by C difficile and MRSA resulted in 1,743 premature deaths in Canada in 2019 and cost hospitals more than $91 million (USD).

One example: ertapenem-resistant Enterobacter cloacae increased significantly in children compared with adults.

A high proportion of broad-spectrum antibiotic use could be replaced by narrower-spectrum or no antibiotic use, researchers report.

Another asymptomatic MERS case reported in a Saudi household contact

The Saudi Arabian Ministry of Health (MOH) today reported another MERS-CoV case involving contact with another patient in Dumah Al Jandal.

It's not known if the new case is related to a hospital outbreak in that city first reported a month ago. The MOH on Aug 30 confirmed two similar MERS-CoV (Middle East respiratory syndrome coronavirus) cases in the same city.

Study: CTX-M-27 gene emerging in clinical E coli isolates in Germany

German researchers have found a significant increase in strains of Escherichia coli carrying a gene linked to extended-spectrum beta-lactamase (ESBL) production, according to a study yesterday in Emerging Infectious Diseases.

New case of MERS in Saudi Arabia linked to camels

The Saudi Arabian Ministry of Health (MOH) noted a new case of MERS-CoV over the weekend in a person who had direct contact with camels, a known risk factor for the virus.

A 57-year-old Saudi man from Hail was diagnosed as having MERS-CoV (Middle East respiratory syndrome coronavirus) after presenting with symptoms of the virus. He is in critical condition.

Precision antimicrobial drug candidate has added benefits, study finds

A team of scientists in the United States and the United Kingdom have identified additional benefits in a new class of antibacterial compounds that specifically kill Clostridium difficile strains without disrupting beneficial bacteria in the gut, according to a study today in Science Translational Medicine.

Study: ESBL-E present in 17% of pregnant, postpartum women in Africa

A systematic review by South African experts yesterday of 10 studies estimates the prevalence of colonization with extended-spectrum beta-lactamase–producing Enterobacteriaceae (ESBL-E) at 17% in pregnant or postpartum African women, higher than women in middle- to high-income settings.

The results represent a risk for colonization of neonates with ESBL-E.

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

Study: ESBL-E present in 17% of pregnant, postpartum women in Africa

A systematic review by South African experts yesterday of 10 studies estimates the prevalence of colonization with extended-spectrum beta-lactamase–producing Enterobacteriaceae (ESBL-E) at 17% in pregnant or postpartum African women, higher than women in middle- to high-income settings.

More children with asthma getting unnecessary antibiotics, study finds

New research presented today at the annual meeting of the European Respiratory Society (ERS) indicates that children with asthma are more likely to be prescribed antibiotics than those without a diagnosis of asthma, even though antibiotics are not recommended for asthma treatment.

BARDA provides $32 million for new C difficile drug candidate

The Biomedical Advanced Research and Development Authority (BARDA) has awarded drug maker Summit Therapeutics $32 million over the next 2 years for development of a new antibiotic for Clostridium difficile infection (CDI).

Study finds no link between US antibiotic prescribing, resistant gonorrhea

Although overuse of antimicrobials is a known contributor to antimicrobial resistance in general, researchers reported yesterday they could find no association between numbers of US antimicrobial prescriptions during a recent 8-year period and resistance in the bacteria that causes gonorrhea.

Specific antibiotics linked to risk of hospital-acquired VRE infections

German researchers have found indications that the risk of acquiring healthcare-associated vancomycin-resistant enterococci (HA-VRE) is linked to the use of specific antimicrobial agents, according to a study yesterday in Antimicrobial Resistance and Infection Control.

Novel assay could help physicians differentiate viral, bacterial infections

Results from a new study in Pediatrics confirmed high performance of a novel diagnostic test to distinguish bacterial from viral infection in febrile children.

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

Novel assay could help physicians differentiate viral, bacterial infections

Results from a new study in Pediatrics confirmed high performance of a novel diagnostic test to distinguish bacterial from viral infection in febrile children.

Study finds subclone is prominent in resistant E coli infections in kids

Researchers at the University of Washington report in Clinical Infectious Diseases that a subclone of the emerging global pathogen Escherichia coli sequence type (ST) 131 is not as prevalent in children as adults but is nearly as dominant in drug-resistant E coli infections in children.

FDA approves new 1-dose antibiotic for treating bacterial vaginosis

Symbiomix Therapeutics announced yesterday that the US Food and Drug Administration (FDA) on Sep 15 approved its antibiotic Solosec (secnidazole) for treating bacterial vaginosis (BV) in adults, the first single-dose option for the condition.

Study finds post-cesarean antibiotics effective in obese women

Postoperative antibiotics more than cut in half the rate of surgical site infection (SSI) within 30 days after delivery among obese women undergoing cesarean delivery, according to the results of a randomized controlled trial published yesterday in JAMA.

Multidrug malaria lineage spreads to Vietnam

A multidrug-resistant parasite lineage that has become dominant in Cambodia, with spread to parts of Thailand and Laos, has now spread to southern Vietnam, where it has been linked to an alarming number of treatment failures in patients who were given the nation's first-line treatment.

FAO calls for One Health stewardship approach, cites success in Cambodia

More funding, public health efforts, and surveillance are needed to ensure responsible use of antimicrobials in food animals and humans, Maria Helena Semedo, deputy director-general with the United Nations (UN) Food and Agriculture Organization (FAO), said yesterday. She was speaking to participants at a UN General Assembly event on Antimicrobial Resistance (AMR).

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

CDC: Cyclospora outbreak tops 1,000 cases 

In an update late last week, the US Centers for Disease Control and Prevention (CDC) said the multistate Cyclospora outbreak now involves 1,031 cases, 43 more cases than in the previous update on Sep 13.