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Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

SHEA survey finds increasing support for hospital stewardship programs

Originally published by CIDRAP News Jul 18

Survey: Antibiotic stewardship often lacking for end-of-life care

A survey of 36 hospitals discovered that about two-thirds had antimicrobial stewardship programs (ASPs) that monitored antimicrobial use in patients during end-of-life care, but only a third had ASPs that offered guidance for patients receiving comfort care only, according to a study today in Infection Control & Hospital Epidemiology.

Massachusetts reports more than 100 Cyclospora cases

Since May 1 state health officials have reported more than 100 cases of Cyclospora infections, compared with 18 to 33 over the previous 3 years, the Massachusetts Department of Public Health (MDPH) said in a news release yesterday.  Other states are also reporting increased cases.

Paper suggests climate change may have aided Candida auris emergence

Could climate change have played a role in the emergence of the multidrug-resistant fungus Candida auris?

Study finds substantial costs, extended hospital stays from C diff

A population-based analysis indicates that hospital-acquired Clostridioides difficile infection (HA-CDI) is associated with millions of dollars in attributable costs and with extended hospital stays, Canadian researchers reported today in Infection Control and Hospital Epidemiology.

Stewardship initiative linked to lower outpatient prescribing in NYC clinics

An effort to reduce inappropriate antibiotic prescribing in New York City hospitals was associated with a modest decrease in prescribing for acute respiratory infections (ARIs), according to a study today in Infection Control and Hospital Epidemiology.

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

Stewardship initiative linked to lower outpatient prescribing in NYC clinics

An effort to reduce inappropriate antibiotic prescribing in New York City hospitals was associated with a modest decrease in prescribing for acute respiratory infections (ARIs), according to a study today in Infection Control and Hospital Epidemiology.

Taco Bell to cut medically important antibiotics in beef supply by 25%

Taco Bell announced yesterday that it aims to reduce the amount of medically important antibiotics used in its US and Canadian beef supply chains by 25% by 2025.

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

Report shows decline in Australian antibiotic use

A report this week from Australian health officials shows a consistent decline in the country's antibiotic use.

WHO experts recommend strains for Southern Hemisphere 2021 flu vaccine

World Health Organization (WHO) flu vaccine advisors recently met to recommend the strains to include in vaccines for the Southern Hemisphere's 2021 season, which—when compared with the Northern Hemisphere upcoming-season version—swaps out the 2009 H1N1 strain.

US public sees frontline workers as first priority for COVID vaccine

A JAMA Network Open survey study of US adults' preferences for COVID-19 vaccine allocation in the event of a limited supply ranks frontline medical workers, high-risk children, and high-risk older adults as highest priority for vaccine distribution.

Review shows stewardship apps increase guideline accessibility

A review of studies analyzing use of antimicrobial stewardship (AMS) apps found they may increase adherence to antibiotic prescribing guidelines, European researchers reported yesterday in PLOS One.

Dutch group recommends restrictive antibiotic use in COVID patients

Based on available evidence and antibiotic stewardship principles, a committee of Dutch clinicians and researchers is recommending restrictive use of antibiotics in COVID-19 patients, according to guidelines published yesterday in Clinical Microbiology and Infection.

Early national study results indicate FMT safe, effective for C diff

Initial results from the FMT (fecal microbiota transplantation) National Registry indicate that FMT is highly effective for treating Clostridioides difficile infection (CDI), with a good safety profile, US researchers reported yesterday in Gastroenterology.

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

CARB-X to fund development of novel antibacterial for pneumonia

CARB-X announced today that it is awarding up to $2.5 million to GangaGen Biotechnologies of Bangalore, India, to develop novel antibacterial proteins to treat hospital-acquired and ventilator-associated pneumonia caused by Klebsiella pneumoniae.

Diagnostic stewardship tied to fewer urine culture orders, hospital UTIs

A diagnostic stewardship program at a large Los Angeles hospital was associated with significantly reduced inpatient urine culture orders and rates of hospital-acquired catheter-associated urinary tract infections (CAUTIs), researchers reported today in Clinical Infectious Diseases.

Hospitalized COVID-19 patients younger, healthier than flu patients

A study yesterday found that US patients hospitalized with COVID-19 are more likely to be male, younger, and have fewer comorbidities and lower medication use than hospitalized flu patients.

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

EU lawmakers urge action on antibiotic shortages, development

Originally published by CIDRAP News Oct 7

European lawmakers yesterday called for the European Union (EU) to address antibiotic shortages and antibiotic development as key components of its forthcoming Pharmaceutical Strategy for Europe.

FDA considers revising criteria for ranking medically important antibiotics

The US Food and Drug Administration (FDA) late last week published a concept paper outlining potential revisions to criteria that the agency uses to guide the use of medically important antimicrobial drugs in veterinary medicine.

CARB-X taps Swiss company to develop antibiotic for Enterobacteriaceae

CARB-X announced today that it is awarding up to $2.62 million to Swiss biopharmaceutical company Polyphor AG to develop a new antibiotic to treat infections caused by Enterobacteriaceae, including carbapenem-resistant Enterobacteriaceae (CRE).

Study will examine risk factors for multidrug-resistant infections

The University of Texas Health Science Center at Houston (UTHealth) announced yesterday that it has received an $11 million grant from the National Institute of Allergy and Infectious Diseases to conduct a 5-year study to better understand why some critically ill patients develop multidrug-resistant infections.

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans

Study will examine risk factors for multidrug-resistant infections

Originally published by CIDRAP News Oct 15

VA study finds increased antibiotic use during early months of COVID-19

Data from inpatient Veterans Administration (VA) hospitals show a significant increase in antibiotic use from January to May, largely negating a downward trend over the previous 5 years, researchers reported today in Infection Control and Hospital Epidemiology.

Cellics receives $3.94 million from CARB-X for sepsis treatment

Today CARB-X announced it is funding $3.94 million to Cellics Therapeutics, based in San Diego, to further its nanomedicine treatment for sepsis.