Maine, which has confirmed only four monkeypox cases, today reported a case of the virus in a resident under the age of 18. No further details were released by the Maine Centers for Disease Control. Maine now joins California and Florida as states with pediatric cases.
Also, researchers in Spain detail a possible human-to-dog case.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
A clinician-directed intervention implemented at facilities in the Veterans' Healthcare Administration (VHA) was associated with better management of, and reduced antibiotic prescribing for, acute respiratory infections (ARIs), researchers reported today in Infection Control & Hospital Epidemiology.
Becton, Dickinson and Company (BD) and Accelerate Diagnostics yesterday announced a commercial collaboration agreement to bring rapid identification and antibiotic susceptibility tests to more clinicians and patients worldwide.
Prescribing data from a children's hospital network in Chicago showed considerable variation in antibiotic durations for children treated for community-acquired pneumonia (CAP) and urinary tract infections (UTIs) in ambulatory settings, with the variability largely unrelated to the severity of symptoms, researchers reported late last week in the Journal of the Pediatric Infectious Diseases Society.
A study of hospitalized pneumonia patients in Denmark found similar outcomes between short-course and prolonged-course antibiotic therapy, Danish researchers reported yesterday in Clinical Microbiology and Infection.
Nonhospitalized, high-risk, vaccinated COVID-19 patients who received nirmatrelvir-ritonavir (NMV-r, or Paxlovid) saw a 45% drop in their relative risk of emergency department (ED) visits, hospitalization, and death by 30 days, suggests a study published late last week in Clinical Infectious Diseases.
A study of electronic health record (EHR) data from a US hospital network found that more than a third of antibiotic prescriptions for uncomplicated urinary tract infections (uUTIs) were inappropriate or suboptimal, researchers reported late last week in Antimicrobial Resistance and Infection Control.
A clinical trial conducted in seven countries found that two shortened, bedaquiline-containing regimens had superior efficacy in treating rifampicin-resistant tuberculosis (TB) compared with a 9-month injectable-containing regimen, with fewer cases of hearing loss, investigators reported today in The Lancet.
A study of more than 3 million patients with bacterial and viral respiratory infections found that inappropriate antibiotic prescriptions were associated with increased risk of adverse events and higher healthcare costs, researchers reported today in Clinical Infectious Diseases.
A study of 97 hospitals in the United States and Canada found that the incidence of urinary tract infection (UTI) and invasive bacterial infection (IBI) in infants with fever fell to pre-pandemic levels by early 2022, researchers reported yesterday in Pediatrics.
The findings suggest the drug could be part of a shorter and simpler tuberculosis treatment regimen.
The percentage of kids receiving 5 to 7 days of antibiotics rose from the baseline of 60% to 86%.
A new report from Scotland's national health service shows that three key healthcare-associated infections remained stable or declined from 2020 to 2021.
Biopharmaceutical company Spero Therapeutics announced today that it has entered into a licensing agreement with GSK for the antibiotic tebipenem pivoxil hydrobromide (HBr).
Swiss biopharmaceutical company Ferring Pharmaceuticals announced yesterday that the Food and Drug Administration's (FDA's) Vaccine and Related Biologic Products Advisory Committee (VRBPAC) voted in favor of the company's investigational fecal microbiota transplant (FMT)-based therapy.
A report published yesterday in Clinical Infectious Diseases describes a new SARS-CoV-2 mutation that confers resistance to the COVID-19 antiviral drug remdesivir in two persistently infected kidney transplant recipients treated with immunosuppressive drugs.
An opt-out protocol for antibiotic de-escalation in patients with suspected sepsis resulted in more antibiotic discontinuations and less exposure to broad-spectrum antibiotics, with no evidence of harm, according to the results of a randomized controlled trial published today in Clinical Infectious Diseases.
A report yesterday from the United Kingdom's Health Security Agency (HSA) shows sexually transmitted Shigella infections are rising again in England after falling during the COVID-19 pandemic.
A multicenter US study identified widespread nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae (CRKP) within and between healthcare settings, researchers reported yesterday in Clinical Infectious Diseases.
