While incidence of community-associated and healthcare-associated community-onset MRSA bacteremia declined during the pandemic, hospital-onset cases rose substantially.
Antibiotic use in the first 3 month of life was associated with a 23% increase in risk of early puberty in girls.
A study of bloodstream infections in Ontario finds attributable mortality due to AMR over 5 years was 896 deaths, or 1.2 per 100,000 population per year.
The AMR Industry Alliance has updated its Antibiotic Manufacturing Standard to be more aligned with WHO antibiotic manufacturing guidelines.
The median treatment duration for uncomplicated gram-negative BSIs at 24 US hospitals was 11 days, with marked variation among hospitals.
Analysis of hospitalized patients with community-acquired pneumonia links azithromycin to lower mortality and more hospital-free days compared with doxycycline in combination with beta-lactams.
Zevtera, an advanced-generation cephalosporin, is available for treating Staphylococcus aureus bacteremia and 2 other types of bacterial infection.
A comparative effectiveness study finds that patients treated with laLGPs had similar outcomes as those who received standard-of-care antibiotics.
The Swiss drugmaker says the safety and efficacy of zosurabalpin will be investigated in a study involving 400 patients with carbapenem-resistant A baumannii infections.
Two novel antibiotic candidates for gonorrhea received funding to advance into clinical trials.
A retrospective analysis of hospitalized VA patients finds that prior flu or RSV infection more than doubled the odds of subsequent Streptococcus pneumoniae infection.
Canadian seniors who received antibiotics within 7 days of a COVID diagnosis were 24% more likely to have an antibiotic-resistant organism within 6 months.
An intervention to promote adherence to 5 days or less of antibiotics for common infections was tied to 6,000 fewer antibiotic-days dispensed per year.
Danish company SNIPR Biome will receive $7.6 million to develop a cocktail of engineered bacteriophages to target Pseudomonas lung infections.
In patients with advanced cancer in South Korea, there was an increase in broad-spectrum antibiotic use from 3 months to 2 weeks before death.
The money will enable biotech company Phiogen to advance its bacteriophage-based treatment and preventive for extraintestinal pathogenic E coli infections.
An experimental study in India finds that even among providers who have knowledge about appropriate antibiotic use, 62% inappropriately prescribed antibiotics for viral child diarrhea.
More than half of ASB cases at five VA outpatient sites were treated with antibiotics.
The center will target prevention strategies for Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae.
Canada's priority pathogens list shows that 45% of the assessed AMR pathogens disproportionately affect marginalized populations and those with structural barriers to health.
Of 37 countries with national action plans, only 3 saw significant reductions in antibiotic sales.
In 2021, China accounted for 14% of global deaths attributable to AMR and 15% of deaths associated with AMR.
The 10-year, $276 million effort aims to strengthen research capacity, promote transnational collaboration, and translate research into practice and policy.
Among 1,000 US respondents, 54% said they weren't familiar with C difficile infection, down from 60% in a 2021 survey.
A review and meta-analysis finds shorter antibiotic courses show similar efficacy for bloodstream infections in immunocompetent patients compared with longer courses.
