The FDA has approved a combo antibiotic that targets complicated urinary tract infections caused by multidrug-resistant bacteria.
CDC scientists report the proportion of carbapenem-resistant Enterobacterales carrying the NDM gene rose from 5% in 2016 to 40% in 2023.
In a survey of healthcare professionals worldwide, 65% said antibiotics could be bought without a prescription in their countries.
Deaths from Staphylococcus aureus–associated lower respiratory tract infections tripled from 1990 to 2021 worldwide.
A clinical trial in Germany finds hand hygiene alone is noninferior to hand hygiene plus gloves and gowns for preventing bloodstream infections in newborns colonized with drug-resistant bacteria.
The findings are from an observational study of more than 15,500 mother-infant pairs.
A review of 13 studies suggests antibiotic courses of 2 to 5 days “may be a reasonable option.”
The Veteran Affairs program uses videoconferencing to connect infectious diseases specialists with rural VA hospitals that don't have ID-trained physicians or pharmacists.
Invasive E coli is the leading cause of sepsis in newborns.
A review of 32 studies suggests increased resources for antimicrobial stewardship programs are associated with improved antimicrobial use and costs.
A study of Medicaid enrollees finds kids with 3 or more complex chronic conditions received more than 5 times as many antibiotics as healthy kids.
An observational study finds amoxicillin-clavulanate provides no benefits over amoxicillin for uncomplicated sinusitis in adults.
In patients who had achieved clinical stability by day 3 of hospitalization, short- and longer-course antibiotic treatments had similar mortality and readmission rates.
The European Commission will invest $34.7 million in the two public-private partnerships to boost the pipeline for new antibiotics and other AMR medical countermeasures.
Researchers say the reduction was influenced by the combined effects of changes in infection prevention and control, antimicrobial stewardship, and health care delivery.
Syphilis cases in the Seattle area fell by 52% overall after the intervention was implemented, but no effect was seen on congenital syphilis.
Research from Argentina suggests use of glyphosate may select for antibiotic-resistant bacteria in soil that could spread to hospitals.
A review and meta-analysis of 19 studies involving 51 cystic fibrosis patients finds bacteriophage therapy was safe and well-tolerated, with improved lung function observed in 74% of patients.
Researchers say the findings reveal an “underrecognized link between climate factors and antibiotic resistance.”
A review and meta-analysis highlights sharply rising resistance to colistin in clinical specimens of Acinetobacter baumannii and Pseudomonas aeruginosa from African countries.
An antibiotic audit and feedback program for Canadian primary care physicians generated more than $30 USD in savings per physician by reducing antibiotic use and antibiotic-associated adverse events.
The guidance aims to help accelerate the development of new antibiotics for severe, drug-resistant gram-negative and gram-positive infections and community-acquired and health care-associated bacterial meningitis.
Although the study relies heavily on unverified reports to an FDA adverse events database, researchers say the findings warrant further investigation.
GARDP has acquired all data and licensing rights for apramycin, an aminoglycoside antibiotic used in veterinary medicine, and will evaluate its potential to treat highly drug-resistant infections in people.
