Smallpox

(CIDRAP News) – An experimental vaccine protected monkeys from the deadly Marburg hemorrhagic fever virus even though they weren't vaccinated until after exposure, according to a report published in the April 29 issue of The Lancet.

(CIDRAP News) – Exactly 100 of about 38,000 civilians who received smallpox shots in a federal program in 2003 suffered serious adverse events afterward, signaling that the program successfully screened out most people at risk for complications, according to a recent report.

(CIDRAP News) – If public health emergency preparedness were a college class, the federal government would be considered a poor pupil by the nonprofit organization Trust For America's Health (TFAH), which gives the government a D+ in a new report released yesterday.

That grade was based on a survey of 20 leading public health experts, who used 12 criteria to measure preparedness.

(CIDRAP News) – The Centers for Disease Control and Prevention (CDC), which recently reconstructed the 1918 pandemic influenza virus for research purposes, has classified the virus as a "select agent," imposing special rules on groups that handle it.

(CIDRAP News) – Hospital residents did poorly on a test of their ability to recognize and manage diseases potentially related to bioterrorism, but they fared much better after taking an online training program, according to a report in Archives of Internal Medicine.

Editor's note: This story was revised Aug 17 to add information on funding and a link to the government's request for proposals to supply the vaccine.

(CIDRAP News) – The US government has called for proposals to supply up to 80 million doses of a weakened smallpox vaccine to protect people for whom the conventional vaccine is too risky, according to two vaccine manufacturers.

Editor's note: This article was revised Aug 15, 2005, to include additional information regarding earlier related research.

(CIDRAP News) – Genetic mutations in monkeypox viruses of West African origin might have spared the lives of people infected with the virus in the United States, according to a recent report.

Though primarily a disease of rodents and nonhuman primates, monkeypox can occasionally spread to humans and cause a smallpox-like illness. In the summer of 2003, an outbreak of the disease occurred in six Midwestern states.

(CIDRAP News) – The Infectious Diseases Society of America (IDSA) is calling the US government's stockpile of antiviral drugs "totally inadequate" in the face of a potential influenza pandemic.

(CIDRAP News) – The influential journal Foreign Affairs is adding its voice to the warnings about a potential influenza pandemic by publishing a special section on pandemics in its forthcoming July/August issue.