Safety profile was good, and sensitivity analysis favored delamanid as part of MDR-TB treatment.
An analysis of Puerto Rican Zika patients who had thrombocytopenia, a rare complication, found that, in those with the severest cases, immune treatments may be more effective than platelet transfusion. A team from the US Centers for Disease Control and Prevention (CDC) and Puerto Rico reported its findings today in Open Forum Infectious Diseases.
Afghanistan officials have reported 3 new cases of wild poliovirus 1 (WPV1), while Papua New Guinea (3 cases), Nigeria (2 cases), and the Democratic Republic of the Congo (DRC, 1 case) have all reported cases involving circulating vaccine-derived poliovirus (cVDPV), according to a weekly update today from the Global Polio Eradication Initiative (GPEI).
An international team of researchers found that the World Health Organization (WHO)-endorsed diagnostic tests for drug-resistant tuberculosis (TB) are missing a substantial number of multidrug-resistant (MDR) TB cases in South Africa. The study appeared yesterday in Lancet Infectious Diseases.
Whole-genome sequencing could lead to faster, more accurate resistance testing.
The US Food and Drug Administration (FDA) today released new draft guidance that spells out when it's appropriate to disclose retail information for recalled products.
A phase 2 study of an adjuvanted subunit vaccine against tuberculosis (TB) in young and middle-aged adults with the latent form of the disease found that it was 54% effective against progression to the active pulmonary form of the disease. An international team led by scientists from GlaxoSmithKline, the vaccine's developer, reported its findings today in the New England Journal of Medicine.
TB remains high in many low- and middle-income nations, and about 558,000 people in 2017 developed rifampicin-resistant TB.
The Nigeria Centre for Disease Control (NCDC) said today it is helping UK officials respond to their two recent monkeypox cases, which involve travelers from Nigeria, a country that has now reported 262 suspected cases.
Newer and repurposed drugs produced better results and fewer deaths than older treatments did.
