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The oral antiviral drug Paxlovid is safe and effective for treating COVID-19 and carries no additional risk of viral rebound beyond other treatments, according to a meta-analysis published late last week in the Journal of Infection.
The US Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are investigating a multistate Listeria outbreak linked to brie and camembert cheeses.
In the past, increasing cases in Europe have come ahead of similar rises in other regions.
Inundated US hospitals held patients in places like hallways for a median of 6.6 hours.
Studies detail viral prevalence in various specimens and tattoo- and healthcare-related spread.
A multicenter US study identified widespread nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae (CRKP) within and between healthcare settings, researchers reported yesterday in Clinical Infectious Diseases.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
Uganda's health ministry on Twitter today reported four more lab-confirmed Ebola Sudan cases, as well as one more death in a patient with a confirmed infection. The developments push the country's overall total to 54 cases, 35 of them confirmed and 19 listed as probable. The latest death brings Uganda's fatality count to 25, 7 in confirmed patients and 18 in people who had probable infections.
Retrospective UK testing reveals a case on Mar 7, two months earlier than previously reported.
Officials add 14 more cases to the total, and the fatality count rises to 24.
The shots offered 74% protection against hospitalization or death and 90% against death alone.
The SARS-CoV-2 Omicron variant is much more transmissible among household members than Delta, with an estimated secondary attack rate (SAR) from thrice-vaccinated index patients of 46%, compared with 11% for Delta, finds a study published today in Nature Communications.
The SAR is the percentage of contacts who become infected by an index (initial) patient.
A report yesterday from the United Kingdom's Health Security Agency (HSA) shows sexually transmitted Shigella infections are rising again in England after falling during the COVID-19 pandemic.
Cases are down 11% worldwide and deaths declined 18%, with the greatest decrease in cases in Africa.
The change was temporary and "within the normal range of variation."
High-flow oxygen didn't significantly lower death rates beyond those of standard oxygen therapy in COVID-19 patients with respiratory failure, according to a multicenter randomized clinical trial published yesterday in JAMA.
An opt-out protocol for antibiotic de-escalation in patients with suspected sepsis resulted in more antibiotic discontinuations and less exposure to broad-spectrum antibiotics, with no evidence of harm, according to the results of a randomized controlled trial published today in Clinical Infectious Diseases.
The Americas house 13% of the world's people, but the region has seen 37% of global cases and 45% of deaths.
Data suggest "boosters continued to provide protection against severe illness despite viral evolution."
A report published yesterday in Clinical Infectious Diseases describes a new SARS-CoV-2 mutation that confers resistance to the COVID-19 antiviral drug remdesivir in two persistently infected kidney transplant recipients treated with immunosuppressive drugs.
