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Forge Therapeutics announced today that it will partner with Hoffman-La Roche to develop and commercialize a novel antibiotic for treating serious lung infections caused by antibiotic-resistant gram-negative bacteria.
The antibiotic, developed by Forge through its Fg-LpxC LUNG program, targets and inhibits LpxC, a zinc metalloenzyme found in gram-negative bacteria, using a proprietary chemistry platform.
More nations, including the UK and India, order countrywide lockdowns.
Italian authors reported a 7.2% fatality rate—even higher in those 70 and older.
New York Governor Andrew Cuomo says the COVID-19 pandemic case count is doubling every 3 days in his state, as the WHO warns that the US could become the next global epicenter.
The WHO urges nations to maintain continuity of TB services as they respond to COVID-19.
The World Health Organization's (WHO's) Special Programme for Research and Training in Tropical Diseases (TDR) announced late last week that 13 projects from 7 countries have been awarded funding for research on antimicrobial resistance (AMR).
In 3 papers, experts lay out strategies for priority decisions on PPE, etc.
Spain seems to be following Italy's trajectory, reporting 4,321 new cases and 33,090 total.
"We need you to understand you could be spreading it to someone else."
Guard troops will help efforts in New York, California, and Washington state.
The FDA authorizes an emergency use authorization for the first point-of-care rapid test.
Italy today reported a staggering 6,000 new cases, and confirmed global deaths have topped 10,000.
The phenotypic tests measure nucleic acid in bacteria after exposure to antibiotics.
Governors in New, California, and Illinois announced new restrictions.
As supplies of equipment dwindle, healthcare workers are likely at increased risk.
There was a sharp uptick last week in US clinic visits for influenza-like illness (ILI), according to the latest FluView report today from the Centers for Disease Control and Prevention (CDC), but CDC officials say that could reflect more people seeking care for respiratory illness as COVID-19 spreads across the country.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
Originally published by CIDRAP News Mar 19
A study today in Infection Control & Hospital Epidemiology reports a high prevalence of antibiotic allergy labels (AALs) in Australian nursing homes.
President Trump is pushing the FDA to remove barriers to using an antimalarial drug.
While kids are less likely than adults to be infected and have severe illness, they are still vulnerable.
Spain, like Italy, has plans to support its overwhelmed health system with medical students and other surge staff.