Over the past 30 days, 88 flocks have been confirmed to be affected by avian flu.
APHIS also reported detections in smaller, backyard poultry flocks in Grady and McClain counties in Oklahoma.
Previous human detections in the US have involved the H5N1 strain.
This is the 18th case of human H5N1 avian flu in Cambodia this year.
The loss may threaten the population's future by reducing the number of surviving pups and highlights the need for continued, intensive monitoring.
If confirmed, it will be the first human bird flu case in the US since February.
In the past 30 days officials have confirmed highly pathogenic avian flu in 31 commercial flocks and 31 backyard flocks across the United States.
In Michigan, 113,000 birds were affected on a turkey farm in Ottawa County, the state's third detection in commercial turkeys in less than a week.
Even without a booster, the vaccine triggered mucosal and systemic immunity, which other intranasal recombinant H5 flu vaccines have not achieved in clinical trials.
Elsewhere, 2 large poultry outbreaks were reported in Lagrange County, Indiana.