Infections are rare and can be severe or fatal, but so far scientists don't see genetic changes that pose an increased threat to people.
Argentina, Bolivia, Guatemala, and Uruguay reported their first highly pathogenic H5N1 detections in different wild bird species.
Species include skunk, raccoon, bobcat, red fox, grizzly bear, black bear, tiger, and mountain lion.
In Cuba, the virus struck wild birds that inhabit a zoo in Havana.
The World Organization for Animal Health notes increasing detections in mammals in recent months, which warrants close monitoring.
The UK mammal H5N1 findings include foxes and otters, part of ongoing detections in mammal species alongside outbreaks in poultry and wild birds.
Commercial turkey farms in Iowa and Virginia were hit, affecting almost 40,000 birds.
US poultry losses have reached a record 58.16 million since the H5N1 outbreaks began in February 2022.
A mutation in the outbreak strain may have public health implications, given that it is present in the 2009 H1N1 pandemic flu virus.
Also, officials detail outbreaks in poultry globally, and 3 more grizzlies are infected in Montana.