The 10 new flu-related deaths in children bring the season's total to 226, the most since 2009-10.
Plaque growth can lead to a higher risk of heart attack, stroke, and other life-threatening cardiovascular events for as long as 1 year.
Post-exertional malaise, or exercise intolerance, was seen in 36% of those with long COVID.
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The study looked at deaths in both Florida and Ohio during the first 22 months of the pandemic.
The effects were equivalent to a 10-year age increase.
Test positivity is higher in some regions, such as the south and west, as Omicron variant proportions show ongoing shift.
The study demonstrates very low levels of resistance to Paxlovid, the antiviral drug most commonly used to treat COVID-19.
A review of 31 studies reveals that long COVID affects 16% of children and adolescents after COVID-19.
This is the first study to assess COVID-related health disruptions on a patient level, the authors said.
The US is one of the countries seeing rising proportions of EG.5, a descendant of the XBB.1.9.2 Omicron subvariant.
The mutation was detected in 20% of study participants who never became sick, compared with 9% of their ill counterparts.
All boosters considered in this study had waning protection, with peak protection at 2 to 4 weeks after injection.
A high risk of obstructive sleep apnea is associated with severe COVID-19 and longer hospitalization.