Over 6 months, COVID infection led to 2.24 extra cases of myocarditis or pericarditis per 100,000 children, versus 0.85 per 100,000 after vaccination.
Plaque growth can lead to a higher risk of heart attack, stroke, and other life-threatening cardiovascular events for as long as 1 year.
Post-exertional malaise, or exercise intolerance, was seen in 36% of those with long COVID.
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Data from a phase 2 randomized controlled clinical trial show ensitrelvir accelerated viral clearance in patients with early symptomatic COVID-19.
The authors noted that viral infections trigger the immune system to release substances that lead to inflammation and increase the risk of blood clots.
The COVID-19 vaccine is unique in having this effect on progression to a chronic condition, despite infection, the researchers say.
Our systematic review published this week shows that rigorous, transparent evidence synthesis can persist even when traditional advisory processes falter.
But the overall odds are likely low and may well have ebbed since the pandemic peak.
The large-scale project was conducted by the Center for Infectious Disease Research and Policy's Vaccine Integrity Project.
Flights from Asia played a larger role in disease spread than those from other countries, the study found.
Overall protection against infections peaked at 4 weeks after vaccination.
The findings underscore the need to explore alternative therapeutic approaches to managing persistent symptoms, the authors say.
Immunocompromised adults and children should receive an age-appropriate COVID-19 vaccine dose as soon as possible, the organization says.
