Pneumonia

Recent News

Sep 21, 2021

Stewardship / Resistance Scan for Sep 21, 2021

Antibiotic use in preterm infants
Probiotics trial
Jul 21, 2021
Women and child in Bangladesh

Drug-resistant pneumonia tied to deaths in Bangladeshi kids

Antibiotic-resistant blood infection in pediatric pneumonia patients was tied to a 17-fold mortality risk.

Jun 18, 2021

Stewardship / Resistance Scan for Jun 18, 2021

Longer than necessary antibiotic prescriptions
Phase 1 trial for new antibiotic
May 20, 2021

News Scan for May 20, 2021

Pneumococcal vaccine and kids' antibiotics
Expert panel on zoonotic diseases
CWD expands in Virginia
Final ground turkey Salmonella update
May 14, 2021

News Scan for May 14, 2021

COVID campus safety ideas
Prepandemic adult vaccination
Vaccine-linked polio in 4 countries
Apr 23, 2021

News Scan for Apr 23, 2021

Malaria vaccine trial
Bacterial coinfections in flu patients
Vegan cheese Salmonella outbreak
Mar 12, 2021
Sick girl in bed with dad taking her temperature

Randomized trial supports shorter antibiotic course for kids' pneumonia

"We should work toward improving care for our patients with right-sized antibiotic courses."

Mar 01, 2021

Stewardship / Resistance Scan for Mar 01, 2021

CARB-X funds for vaccines
VA sputum susceptibility
Oct 20, 2020

Stewardship / Resistance Scan for Oct 20, 2020

VA antibiotic use during COVID-19
Shorter pneumonia therapy
Oct 13, 2020
Antibiotic-resistant superbugs

Phase 3 trials show positive results for cefiderocol, but questions remain

Two studies show the new antibiotic is safe and effective for difficult-to-treat MDR infections.

Resources & Literature

Recent Literature

Africano HF, Serrano-Mayorga CC, Ramirez-Valbuena PC, et al. Major adverse cardiovascular events during invasive pneumococcal disease are serotype dependent. Clin Infect Dis 2020 (published online Sep 22)

Agudelo CI, Castaneda-Orjuela C, Brandileone MC, et al. The direct effect of pneumococcal conjugate vaccines on invasive pneumococcal disease in children in the Latin American and Caribbean region (SIREVA 2006–17): a multicentre, retrospective observational study. Lancet Infect Dis 2020 (published online Sep 25)

Albin OR, Kaye KS. Utility of radiographic keyword abstraction for identification of misdiagnosed pneumonia. Infect Control Hosp Epidemiol 2021 (Concise communication) (published online Apr 29)

Arias-Fernandez L, Montero JSR, Gil-Prieto R et al. Burden of pneumonia in patients with viral and bacterial coinfection in Spain during six consecutive influenza seasons, from 2009-10 to 2014-15. Vaccine 2021 (published online Jul 23)

Baron SA, Cassir N, Hamel M, et al. Risk factors for acquisition of colistin-resistant Klebsiella pneumoniae and expansion of a colistin-resistant ST307 epidemic clone in hospitals in Marseille, France, 2014 to 2017. Eurosurveill 2021 May 27;26(21)

Bartley PS, Deshpande A, Yu PC, et al. Bacterial coinfection in influenza pneumonia: Rates, pathogens, and outcomes. Infect Control Hosp Epidemiol 2021 (published online Apr 23)

Ben-Shimol S, Givon-Lavi N, Kotler L, et al. Post–13-valent pneumococcal conjugate vaccine dynamics in young children of serotypes included in candidate extended-spectrum conjugate vaccines. Emerg Infect Dis 2021 Jan;27(1)

Camara J, Grau I, Gonzalez-Diaz A, et al. A historical perspective of MDR invasive pneumococcal disease in Spanish adults. J Antimicrob Chemother 2020 (published online Nov 30)

Carey E, Blankenhorn R, Chen P, et al. Non-ventilator associated hospital acquired pneumonia incidence and health outcomes among U.S. veterans from 2016-2020. Am J Infect Control 2021 (published online Jun 8)

Carr OJ, Vilivong K, Bounvilay L, et al. Nasopharyngeal pneumococcal colonization Density is associated with severe pneumonia in young children in the Lao PDR. J Infect Dis 2021 (published online May 11)

Chen D, Ye Z, Pi Z, et al. Cost-effectiveness of dual influenza and pneumococcal vaccination among the elderly in Shenzhen, China. Vaccine 2021 (published online Mar 20)

Chen H, Matsumoto H, Horita N, et al. Prognostic factors for mortality in invasive pneumococcal disease in adult: a system review and meta-analysis. Sci Rep 2021 Jun4;11:11865

Chen IR, Huanag PH, Wu PF, et al. Clinical characteristics and outcomes of 56 patients with pneumonia caused by carbapenem-resistant Klebsiella pneumoniae. J Glob Antimicrob Resist 2021 (published online May 4)

Chen Z, Wu H, Jiang J, et al. Nutritional risk screening score as an independent predictor of nonventilator hospital-acquired pneumonia: a cohort study of 67,280 patients. BMC Infect Dis 2021 Apr 1;21:313

Chhatwal J, Sapru A, Sundaram B, et al. A phase 4 study of the safety of the 13-valent pneumococcal conjugate vaccine in children 6 to 17 years of age in India. Vaccine 2021 (published online Aug 6)

Clarke E, Bashorun A, Adigweme I, et al. Immunogenicity and safety of a novel ten-valent pneumococcal conjugate vaccine in healthy infants in the Gambia: a phase 3, randomised, double-blind, non-inferiority trial. Lancet Infect Dis 2021 (published Jan 28)

Cury VF, Antoniazzi LQ, de Oliveira PH, et al. Developing the pneumonia-optimized ratio for community-acquired pneumonia: an easy, inexpensive and accurate prognostic biomarker. PLoS One 2021 (published online Mar 23)

D'Mello A, Riegler AN, Martinez E, et al. An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease. Proc Natl Acad Sci 2020 Dec 29;117(52):33507-18

Dagan R, Ben-Shimol S, Benisty R, et al. A nationwide outbreak of invasive pneumococcal disease in Israel caused by Streptococcus pneumoniae serotype 2. Clin Infect Dis 2020 (published online Nov 17)

De Miguel S, Domenech M, Gonzalez-Camacho F, et al. Nationwide trends of invasive pneumococcal disease in Spain (2009-2019) in children and adults during the pneumococcal conjugate vaccine era. Clin Infect Dis 2020 (published online Sep 29)

Desmet S, Wouters I, van Heirstraeten L, et al. In-depth analysis of pneumococcal serotypes in Belgian children (2015–2018): diversity, invasive disease potential, and antimicrobial susceptibility in carriage and disease. Vaccine (published online Dec 9)

Dinh A, Ropers J, Duran C, et al. Discontinuing beta-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo-controlled, non-inferiority trial. Lancet 2021 (published online Mar 27)

Dion SB, Major M, Grajales AG, et al. Invasive pneumococcal disease in Canada 2010-2017: the role of current and next-generation higher-valent pneumococcal conjugate vaccines. Vaccine 2021 (published online Apr 3)

Do NT, Li R, Dinh HT, et al. Improving antibiotic prescribing for community-acquired pneumonia in a provincial hospital in Northern Vietnam. JAC Antimicrob Resist 2021 Jun;3(2)

Eythorsson E, Asgeirsdottir TL, Erlendsdottir H, et al. The impact and cost-effectiveness of introducing the 10-valent pneumococcal conjugate vaccine into the paediatric immunisation programme in Iceland—a population-based time series analysis. PLoS One 2021 (published online Apr 8)

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