In a flu pandemic setting, the drug could be used to curb household transmission, especially early in the response, the authors say.
The loss of activity is equivalent to 15% of the US population becoming completely immobile for 1 day.
Adult COVID-19 patients also infected with the flu are 4 times more likely to need mechanical ventilation and 2.4 times more likely to die.
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CD388 is Cidara's novel drug for preventing flu in adults at high risk for severe influenza, including those for whom vaccines are either ineffective or not indicated.
Flu and RSV levels are rising to prepandemic levels, with increasing hospitalizations in children younger than 2 years.
Some Southern Hemisphere countries such as Australia and Chile are reporting increased influenza activity.
Even those who did 10 to 150 minutes of aerobic (cardio) exercise per week had a 21% lower risk, with higher levels linked to a 41% to 50% reduction.
COVID-19 patients had a longer hospital stay and a 69% higher mortality rate than ICU patients with influenza.
As flu levels taper off in the Northern Hemisphere, some Southern Hemisphere nations have reported increased detections in recent weeks.
After a rise in flu activity in late January, led mainly by the 2009 H1N1 strain and influenza B, levels are declining again.
RSV activity began in the southeast and worked its way north and west. In its Marburg notice, the CDC said there is no evidence so far that the two outbreaks are connected.
Investigators are working to determine the Chilean man's H5N1 exposure, and in Senegal, H5N1 has now infected a poultry flock.
Nearly two-thirds of patients hospitalized with flu, RSV, or COVID-19 received antibiotics, but they had a higher risk of death than those who didn't.
