Study finds no risk of pregnancy loss after receiving flu vaccine
Emory researchers found that pregnant women who received a flu vaccine had a lower risk of stillbirth than unvaccinated women, according to a study published yesterday in Clinical Infectious Diseases. The meta-analysis also found no association between miscarriage and receiving a flu vaccine.
Pregnant women are at high risk for influenza infection and complications, and the US Centers for Disease Control and Prevention recommends vaccination at any point during pregnancy. Despite recommendations, many women have concerns about vaccination's effects on pregnancy and fetal health.
In a review of seven studies, researchers found a statistically significant decreased risk of stillbirth among vaccinated women (relative risk [RR], 0.73). Stillbirth risk was slightly lower among women vaccinated with the 2009 H1N1 pandemic vaccine (RR, 0.69), and no association was found between stillbirth and receipt of the 1976 monovalent seasonal H1N1 vaccine. The study likewise found no association between risk of miscarriage and vaccination.
Only one study used in this review evaluated risk associated with a non-pandemic vaccine. Due to this limitation, the authors acknowledged the need for more research on associations between pregnancy outcomes and seasonal trivalent flu vaccines.
Nov 18 Clin Infect Dis study
UK's Flusurvey to include home testing this season
For the first time, some people participating in Britain's Flusurvey, the country's largest crowd-sourced influenza study, will be offered a free kit for obtaining a nasal swab to confirm whether their influenza-like illness (ILI) is caused by influenza, the London School of Hygiene & Tropical Medicine (LSHTM) said in a press release yesterday.
Swabs will be sent to a representative sample of 700 Flusurvey participants, who fill out a weekly symptom questionnaire. If the volunteers report an ILI, they will swab themselves at home and see results in minutes—much as with a home pregnancy test, according to the release. They will submit their results via e-mail and mail the test to a Public Health England (PHE) lab for verification.
The number of positive tests received each week will be compared with figures obtained by primary care–based virologic sampling coordinated by PHE.
LSHTM researchers analyze weekly Flusurvey data to monitor influenza activity. They team with PHE and i-sense, an interdisciplinary research collaboration, to compare this information with the results of swab samples and with "big data" on millions of symptoms reported every day via sources such as Twitter, the school said in the press release.
Nov 18 LSHTM press release