A report from the GLG includes 6 recommendations aimed at incentivizing innovation, stimulating R&D efforts, and ensuring access to antibiotics.
While the FDA did not identify clinical safety or efficacy issues with the combination antibiotic, it asked for more information about manufacturing processes.
A systematic review and meta-analysis found that women with Staphylococcus aureus bacteremia had an 18% increased mortality risk compared with men.
The first-in-class, novel antibiotic showed non-inferiority to the current standard-of-care gonorrhea treatment.
Patients undergoing gastrointestinal surgery at safety net hospitals had a nearly 30% increased risk of SSIs compared with all hospitals.
Of the 135 isolates, 55% were identified as containing multi-drug resistant E coli.
Danish research and development company GlyProVac will receive $467,000 to develop a maternal vaccine that targets a leading cause of neonatal sepsis.
The report calls for progress in 4 key areas: antibiotic manufacturing, antibiotic research and development, access, and appropriate use.
Since 2016, CARB-X has awarded $452 million for early-stage development of antibacterials and other products targeting drug-resistant bacteria.
Researchers say preoperative urine cultures provide little value and lead to unnecessary and potentially harmful antibiotic use.
Only 37% of infectious diseases practitioners said their facility screens patients for the drug-resistant fungus.
Gonorrhea cases in EU/EEA countries rose by 48%, syphilis cases by 34%, and chlamydia cases by 16% in 2022.
The study authors say cutting down on repeat within-episode antibiotic prescriptions for RTIs could represent a 'quick win' for antimicrobial stewardship.
Children in certain racial and ethnic groups were more likely to receive broad-spectrum antibiotics for acute respiratory infections than White children.
A literature review found pneumococcal conjugate vaccines were associated with some protection against flu and other viral respiratory tract infections.
Researchers say the data support guidelines that recommend withholding antibiotic treatment for asymptomatic bacteriuria.
Researchers say the introduction of typhoid conjugate vaccines in these countries could help protect communities, especially school-aged children.
Increased investment in TB control and prevention has helped reduce incidence in young people, but incidence of drug-resistant TB is rising.
Increasing pneumococcal vaccination in communities that face health inequities could help, the study's authors say.
Clinical trial and real-world data indicate the pneumococcal conjugate vaccine candidate V116 covers the serotypes responsible for most pneumococcal disease in older adults.
Receipt of the MMR vaccine was associated with an 11% reduced rate of antibiotic treatment in children under 2.
The excess deaths are attributed to pandemic-related disruptions to TB services, which resulted in more people with undiagnosed and untreated TB.
The company says it will allow use of animal antibiotics in its chicken supply, but not antibiotics that are also used in human medicine.
Among participants from Finland and the Netherlands, a greater abundance of butyrate-producing bacteria in the gut was linked to reduced risk of hospitalization from infection.
Company officials say the rapid PCR test could aid antimicrobial stewardship efforts.
