The $3.5 million award will support development of Melio's rapid, culture-free diagnostic testing platform.
The trial, conducted in the United Kingdom, found that a procalcitonin-guided algorithm didn't reduce IV antibiotic duration when compared with usual care.
Among 547 episodes of C difficile infection documented in cancer patients in Australia and Spain, 50% were severe, and the 90-day recurrence rate was 16%
Shionogi will receive $375 million to develop a long-acting protease inhibitor designed to prevent SARS-CoV-2 infection in people who are immune compromised.
In patients with catheter-associated asymptomatic bacteriuria caused by multidrug-resistant Pseudomonas, antibiotic treatment was a significant risk factor for subsequent infection.
The money will help maintain and expand AMR dashboards that focus on tracking the emergence and spread of drug-resistant microbes in domesticated animals.
Sales of antibiotics for use in food-producing animals in the United Kingdom have fallen by 59% since 2014, according to the latest UK-VARSS report.
Researchers estimate vaccines for enteric pathogens could prevent up to 8 to 12 courses of antibiotics per 100 vaccinated children per year in low-resource countries.
The percentage of long-term care residents receiving an antibiotic decreased from 51% to 44% from 2013 to 2021.
Analysis of clinical isolates of E coli ST131 identified 18 different carbapenemase genes, which could limit treatment options.
Exposure to certain antibiotic classes before pregnancy was associated with increased risk of infertility, miscarriage, and congenital malformation.
The partnership will evaluate the clinical need and address market barriers for diagnostic, therapeutic, and preventive interventions for gonorrhea in low-resource countries.
Researchers found that more than two thirds of patients with negative chest x-rays received antibiotics.
The odds of receiving first-line antibiotic therapy at pediatric urgent care centers were lower in White children and those with commercial insurance.
A population-wide cohort study in Ontario finds that more than 15% of residents colonized with resistant bacteria went on to develop an infection with the same organism.
Use of audit and feedback reports at 2 children's hospitals was associated with a 32% increase in the rate of appropriate antibiotic choice and duration for community-acquired pneumonia.
But the risk of bacterial infections in COVID-19 patients was substantially elevated after 48 hours compared with the other viruses.
The strain of XDR Shigella sonnei, found in 3 men, is distinct from other globally circulating strains.
Data from US pharmacies indicates the volume of outpatient antibiotic prescriptions, after falling sharply in 2020 and 2021, rose to 2019 levels by the end of 2022.
Researchers say sepsis-related mortality is the underlying cause of the disparity.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
New guidelines from the American Dental Association (ADA) recommend against using antibiotics for toothaches in most cases.
A study today in Infection Control & Hospital Epidemiology has determined that an electronic best practice advisory combined with prescriber education was associated with reduced antibiotic prescribing for adults with acute bronchitis.
US acute care hospitals saw significant declines in ventilator-associated events, along with central line- and catheter-associated infections.
Researchers found that a strategy based on patient risk factors had higher rates of appropriate therapy and reduced antibiotic overuse.
Studies conducted in 29 African countries showed the overall pooled prevalence of Shigella bacteria was 5.9%, with concerning levels of antibiotic resistance.
