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Twenty-three European nations have seen a rise in carbapenem-resistant Klebsiella pneumoniae bloodstream infections since 2019.

Overall, 45.8% of COVID-19 hospital admissions and 51.2% of admissions for other respiratory viruses received at least one dose of antibiotic from March 2020 through December 2023.

The findings contradict a 2018 Food and Drug Administration warning that fluoroquinolone use could increase the risk of aortic aneurysm or dissection.

AstraDx will receive $3 million to develop a test that detects and identifies pathogens and analyzes antimicrobial susceptibility in whole blood drawn from newborns.

The rate of gonorrhea cases across Europe rose by 31% in 2023 compared with 2022, and is up 321% since 2014.

The global research agenda includes 33 research priorities for bacterial and fungal infections and 7 for drug-resistant tuberculosis.

Pearl Diagnostics will receive $1 million to evaluate the potential of a prototype assay for early detection of pneumonia caused by Pseudomonas aeruginosa.

Emblaveo (aztreonam-avibactam) was approved for treating complicated intra-abdominal infections with limited or no treatment options.

Frequent interactions between antimicrobial stewardship physicians and pharmacists and use of local antibiotic prescribing guidelines were tied to less antibiotic use at discharge.

The Bill & Melinda Gates Foundation, Novo Nordisk Foundation, and Wellcome are collaborating on a $50 million effort to boost discovery of novel antibiotics for gram-negative bacteria.

Review of data from the trial found that the vaccine was not sufficiently effective at preventing invasive E coli disease compared with placebo. 

Analysis of data from 537 US hospitals reveals that ceftolozane-tazobactam and ceftazidime-avibactam are the most frequently used new antibiotics.

Among patients prescribed doxycycline post-exposure prophylaxis, cases of syphilis, chlamydia, and gonorrhea fell by 86.4%. 89.7%, and 54.7%, respectively.

Researchers say interventions to reduce RSV infections, like vaccines and monoclonal antibodies, could aid antibiotic stewardship efforts.

In a study in Belarus and Uzbekistan, 96% of patients with drug-resistant TB who received the regimens had successful treatment outcomes.

Biggest US outbreak of highly resistant bacteria tied to Illinois hospital

The largest US outbreak so far of bacteria producing the enzyme NDM (New Delhi metallo-beta-lactamase), which confers resistance to most antibiotics, has been linked to a Chicago area hospital, according to the Chicago Sun-Times and the Centers for Disease Control and Prevention (CDC). The contamination was traced to endoscopic equipment.

Scientists create possible early-stage MERS-CoV vaccine candidate

Using reverse genetics, Spanish researchers have created a full-length DNA clone of the MERS-CoV virus that could be used as a vaccine candidate and to study characteristics of the virus, the team reported today in mBio, published by the American Society for Microbiology (ASM).

Dengue cases in Martin County, Florida, reach 18

Martin County, Florida, today confirmed 3 more dengue infections to bring the county's total to 18, The Global Dispatch reported, as a blood center suspended collections in Martin County and neighboring St. Lucie County.

Cyclospora total climbs to 675

The nation's Cyclospora outbreak total has risen to 675, based on an update today from the US Centers for Disease Control and Prevention (CDC) plus additional cases in the latest update from Texas, the state reporting the most cases.

Donald Low, MD, Canadian SARS leader, dies at 68

Donald E. Low, MD, who became Canada's public face of SARS 10 years ago, died last night, according to media reports and Mount Sinai Hospital in Toronto, where he headed the microbiology department until recently.

Study: Flu vaccine effectiveness may drop within a few months

The effectiveness of the influenza vaccine dropped from 52% at 3.5 months after vaccination to 22% more than 4 months after vaccination during the 2011-12 season, according to a study out of Spain today in BMC Infectious Diseases whose power was limited by a small sample size.

Colorado cantaloupe farmers from 2011 Listeria outbreak face trial

The owners of Colorado's Jensen Farms, source of contaminated cantaloupes blamed for a widespread Listeria outbreak in 2011, have been arrested on misdemeanor charges of introducing adulterated food into interstate commerce, according to an Associated Press (AP) story yesterday.

Study: Vaccine exemptions helped fuel California pertussis outbreak

Clusters of children who had nonmedical exemptions (NMEs) from vaccines appears to be one of several factors that played a role in California's 2010 pertussis (whooping cough) epidemic, researchers reported today in Pediatrics.

Norovirus vaccine reduced symptoms in challenge study

A vaccine targeting two common norovirus strains reduced vomiting and diarrhea and prevented severe illness in a small clinical challenge study, researchers reported today at the IDWeek conference in San Francisco.

Indonesia confirms H5N1 death

Indonesia's Ministry of Health has confirmed the country's second H5N1 case this year, in a 28-year-old man from Bekasi.

The man died from the disease, according to a machine-translated health ministry statement today on FluTrackers, the Web-based infectious disease message board. The health ministry statement is dated Oct 3.