San Diego health officials warn of possible TB exposure at a high school during the 2023-24 academic year.
Investigators with the endTB trial say the 9-month, all-oral drug regimens will make it easier for patients with rifampicin-resistant TB to complete the full treatment.
Sixty-seven active TB cases and 79 latent TB cases have been reported in 2 Kansas counties since the beginning of 2024.
With a total of $100 billion spent, PEPFAR is the largest public health commitment in history by any country to address a single disease.
Genomic analysis identified strains of multidrug-resistant TB with additional resistance to the 6-month BPaL/M treatment regimen.
The guidelines recommend a 4-month drug regimen for adults and children with drug-susceptible TB, and a 6-month regimen for those with drug-resistant TB.
A meta-analysis of data from two trials found 6 months of levofloxacin in kids and adults exposed to MDR-TB was associated with a 60% relative reduction in TB incidence.
The Xpert MTB/RIF Ultra test is the first TB diagnosis test to meet the WHO's prequalification standards.
Researchers find that 10% of children living in an area of high TB transmission developed TB disease by the age of 10.
The report also spotlights the urgency of vaccines for pathogens such as group A Streptococcus and Klebsiella pneumoniae, which are increasingly resistant to antimicrobials.