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Two doses of the Pfizer/BioNTech and Moderna mRNA COVID-19 vaccines were 93% and 96% effective, respectively, in preventing severe, critical, or fatal disease caused by the highly transmissible Delta (B1617.2) variant, a study today in Nature Medicine finds.
Among children with community-acquired pneumonia (CAP) who were discharged from the hospital within 48 hours but required further outpatient treatment, a lower dose of oral amoxicillin was non-inferior to a higher dose, and a 3-day duration was non-inferior to 7 days, according to the results of a randomized clinical trial published today in JAMA.
The group agreed on a goal of vaccinating at least 70% of the world's population by the middle of next year.
A pair of values-based incentive programs at US hospitals were linked to a decline in C difficile.
"As we await CDC's decision, we are not waiting on operations or logistics."
A third Pfizer COVID-19 vaccine dose is 92% more effective in reducing severe COVID-related outcomes than two doses of the same vaccine received at least 5 months previously, according to a large real-world study late last week in The Lancet.
Antibiotic prescribing during the early COVID-19 months in Canada dropped sharply, according to two new studies, one that looked at retail pharmacy trends across the country and one that focused on outpatient prescribing patterns in Ontario.
The acting FDA chief says the move will bring us closer to a sense of normalcy.
The secondary attack rate was 25% in fully vaccinated people and 38% in the unvaccinated.
The authors say all eligible people should get the vaccine ASAP, including those previously infected.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
Originally published by CIDRAP News Oct 28
Yesterday, the Centers for Disease Control and Prevention (CDC) added 1 case and 3 hospitalizations to a multistate Salmonella outbreak—now at 21 cases—tied to salami sticks sold at Trader Joe's and Wegmans, and earlier this week the agency declared its investigation into a Salmonella outbreak tied to Italian-style meats over after 40 cases in 17 states.
Cancer patients who received systemic treatment like chemotherapy or radiation in the 3 months before testing positive for COVID-19 were at increased risk of death, admission to an intensive care unit (ICU), and hospitalization, according to a study yesterday in JAMA Oncology.
Also, a syringe shortage looms, and African nations lag woefully in COVID-19 vaccine uptake.
Of parents polled, 30% will definitely not get their child vaccinated, and 33% will wait and see.
The cheap drug fluvoxamine reduced the need for a long emergency department visit or a hospital stay.
Use of a rapid diagnostic test in patients with bloodstream infections (BSIs) was associated with shorter times to optimal antibiotic therapy and antibiotic de-escalation, researchers reported yesterday in Clinical Infectious Diseases.
The monoclonal antibody sotrovimab reduced the risk of hospitalization or death from COVID-19 by 85% compared with placebo, according to an interim analysis of a phase 3 clinical trial published yesterday in the New England Journal of Medicine.
CDC director says the nation is "now heading in the right direction, but needs to remain vigilant."
An agreement with the UN eases access in low- and middle-income countries to molnupiravir.
