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Cefiderocol has a novel way of penetrating the outer membrane of gram-negative bacteria, including resistant ones.
According to the latest weekly update from the Global Polio Eradication Initiative (GPEI), both Pakistan and Afghanistan recorded new polio cases in the past week.
Pakistan has two new cases of wild poliovirus type 1 (WPV1), in Sindh and Khyber districts. The case-patients experienced onset of paralysis on Sep 22 and 25, respectively. Officials have now reported six WPV cases in Pakistan this year, one more than at this time in 2017.
A Swedish study has found that a hospital stewardship program that restricted cephalosporin use was tied to reduced rates of Clostridioides difficile infection (CDI).
The new law would generally limit use of antibiotics to prevent disease in individual animals.
In its daily update today the Democratic Republic of the Congo (DRC) health ministry reported four more lab-confirmed cases, three in the current outbreak epicenter in Beni and one in the city of Butembo.
An investigation into 40 variant H3N2 (H3N2v) influenza cases in people exposed to pigs at three agriculture fairs in Maryland in September 2017 found that 30 (75%) occurred in people at high risk for flu complications. Researchers from the US Centers for Disease Control and Prevention and Maryland described their findings today in Morbidity and Mortality Weekly Report (MMWR).
Bacterial reads for unexplained sepsis were 1,000 times higher than with a different assay.
The Democratic Republic of the Congo (DRC) confirmed three more cases of Ebola and recorded two new deaths in the ongoing outbreak in North Kivu province.
Two of the new cases and both deaths occurred in Beni, the hots pot of the outbreak that saw violent attacks by rebel forces over the weekend. One new case was recorded in Butembo.
Today the US Food and Drug Administration (FDA) approved Xofluza (baloxavir marboxil) for the treatment of flu in patients ages 12 years and older who have been symptomatic for no more than 48 hours.
Xofluza is the first novel flu treatment approved by the FDA in nearly 20 years; the FDA approved the neuraminidase inhibitors oseltamivir and zanamivir in 1999.
Report calls for more aggressive action to reduce unnecessary antibiotic use and promote antibiotic development.
Health officials are probing why a disproportionate number of children are among the recent cases in Beni.
In an update today, the Centers for Disease Control and Prevention (CDC) announced 63 more cases of Salmonella illnesses connected to tainted beef products from JBS Tolleson, Inc. The outbreak, caused by the Newport strain of the bacterium, now stands at 120 cases in 22 states.
In avian flu outbreak developments, the United States reported the detection of low-pathogenic H5N2 in a Minnesota turkey flock and Laos reported a highly pathogenic H5N1 outbreak in backyard birds.
Eight of the new cases are in Beni, including 5 of the 6 fatal illnesses.
Experts hope the move will aid future antibiotic discovery.
In an update today, the US Centers for Disease Control and Prevention (CDC) said state and federal health partners are investigating 28 more suspected acute flaccid myelitis (AFM) cases, raising the overall number of patients under investigation to 155.
The antibiotic prescribing component of a financial incentive program to improve services at UK National Health Service (NHS) clinics found a significant reduction in both total and broad-spectrum antibiotic prescribing in primary care settings, with no link to unintended consequences, except for a few specific conditions.
The CDC started its reporting for the new flu season last week, and so far most of the United States is experiencing sporadic flu detections.
Today the Democratic Republic of the Congo (DRC) announced four more confirmed cases of Ebola virus in Beni, the current epicenter of the outbreak in North Kivu province.
Officials also recorded three new deaths in Beni, including two community deaths that had safe and dignified burials.
