CIDRAP newsletters options
In the past, increasing cases in Europe have come ahead of similar rises in other regions.
Uganda's health ministry on Twitter today reported four more lab-confirmed Ebola Sudan cases, as well as one more death in a patient with a confirmed infection. The developments push the country's overall total to 54 cases, 35 of them confirmed and 19 listed as probable. The latest death brings Uganda's fatality count to 25, 7 in confirmed patients and 18 in people who had probable infections.
A multicenter US study identified widespread nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae (CRKP) within and between healthcare settings, researchers reported yesterday in Clinical Infectious Diseases.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
The shots offered 74% protection against hospitalization or death and 90% against death alone.
Retrospective UK testing reveals a case on Mar 7, two months earlier than previously reported.
Officials add 14 more cases to the total, and the fatality count rises to 24.
The SARS-CoV-2 Omicron variant is much more transmissible among household members than Delta, with an estimated secondary attack rate (SAR) from thrice-vaccinated index patients of 46%, compared with 11% for Delta, finds a study published today in Nature Communications.
The SAR is the percentage of contacts who become infected by an index (initial) patient.
A report yesterday from the United Kingdom's Health Security Agency (HSA) shows sexually transmitted Shigella infections are rising again in England after falling during the COVID-19 pandemic.
Cases are down 11% worldwide and deaths declined 18%, with the greatest decrease in cases in Africa.
The change was temporary and "within the normal range of variation."
An opt-out protocol for antibiotic de-escalation in patients with suspected sepsis resulted in more antibiotic discontinuations and less exposure to broad-spectrum antibiotics, with no evidence of harm, according to the results of a randomized controlled trial published today in Clinical Infectious Diseases.
High-flow oxygen didn't significantly lower death rates beyond those of standard oxygen therapy in COVID-19 patients with respiratory failure, according to a multicenter randomized clinical trial published yesterday in JAMA.
Data suggest "boosters continued to provide protection against severe illness despite viral evolution."
The Americas house 13% of the world's people, but the region has seen 37% of global cases and 45% of deaths.
A report published yesterday in Clinical Infectious Diseases describes a new SARS-CoV-2 mutation that confers resistance to the COVID-19 antiviral drug remdesivir in two persistently infected kidney transplant recipients treated with immunosuppressive drugs.
Illnesses have been reported in 2 more locations.
Three doses of an mRNA vaccine were tied to a 59% lower odds of hospital care than 2 doses.
A new study based on COVID-19 patients in France shows high reinfection rates among people with different Omicron subvariants, including BA.1, BA.2, and BA.5. The study is published as a research letter in Emerging Infectious Diseases.
According to a new non-peer reviewed study out of Israel, the Jynneos vaccine is 79% effective against monkeypox infection.
The study was based on patients eligible for monkeypox vaccine seen in the Clalit Health Services system between Jul 31 and Sep 12, 2022. Of 1,970 subjects eligible for the study, 873 (44%) were vaccinated with Jynneos and completed at least 25 days of follow-up.
