Because not all viruses from mpox cases are sequenced, the findings likely underestimate the prevalence of the newly identified drug-resistant variant.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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The current DRC outbreak has already claimed 581 lives.
This is the country's first outbreak defined by sexual transmission, with several early cases documented in sex workers.
The emergency team also treated patients with measles, malnourishment, and malaria.
Serial scores matched clinical observations, and MPOX-SSS demonstrated good discrimination, identified changes over time, and generated higher scores in the expected groups.
Most of the newly affected Finnish farms raised foxes, but some also produced raccoon dogs.
Of the 1,124 mpox patients, 44% had HIV, and 70% had a previous or current sexually transmitted infection.
A total of 39% to 54% reported no change in these behaviors, and less than 1% reported an increase.
Today's recommendation also sets the stage for transition to the commercial market in the months ahead.
Europe had the biggest mpox rise in September, though the Western Pacific region continues to report the highest levels.
The frequency of resistant isolates remains relatively low compared to the number of patients treated with the drug.
