In DRC hot spots, vaccination will target the greater community, not just contacts. A trial of the antiviral drug brincidofovir also launched in the country.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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The FDA upgraded a voluntary recall of organic, pasture-raised eggs sold by Costco stores to Class I, the agency's highest risk level, over Salmonella concerns.
Belgium reported the case on December 18 in an adult traveler returning from an African country where the clade 1b virus circulates.
Two African countries reported more circulating vaccine-derived poliovirus type 2 cases.
Africa CDC shared findings from a review of the response and said doses of the LC16 vaccine from Japan will arrive this week.
Germany had reported one other clade 1b case in October, and the patient recovered fully.
Activity continues to fluctuate across different countries, with cases of novel clade 1b continuing to rise.
The study's safety board recommended halting enrollment after an assessment showed the chance was less than 1% that the study would demonstrate efficacy if completed.
Recent detections in Zimbabwe and Zambia were confirmed as the novel 1b clade.
UK health officials said the overall threat to the UK population remains low.
Seven countries outside of Africa have now reported imported clade 1b cases.
