Despite declines in 2 high-burden countries, cases are rising in Burundi, Uganda, Ghana, Kenya, Liberia, and Guinea.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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The freeze-dried formulation will be easier to store and transport than the liquid-frozen formulation that Bavarian Nordic has been supplying to the US government.
Healthcare workers remain the most trusted sources of information (73%), while trust in the federal government to provide factual information rose to 58%.
Some of the key steps have included deployment of more community health workers and decentralized lab testing.
The cases in Malawi bring the number of African countries affected by mpox to 23.
Cases are declining in some hot spot countries, as officials warns that nations outside Africa are still reporting imported cases.
The median number of days to lesion clearance was 7 with Tpoxx and 8 with placebo.
In Uganda, the virus is spreading in urban areas and among sexual networks, posing contact-tracing challenges.
Clade 1b is fueling a central Africa mpox outbreak, with the Democratic Republic of the Congo seeing the most cases.
Earlier patients had traveled to outbreak countries or were contacts of earlier cases.
Ghana reported its first recurrence in many weeks, as cases rise in Tanzania and responders launch a second vaccination round in Uganda.
