In DRC hot spots, vaccination will target the greater community, not just contacts. A trial of the antiviral drug brincidofovir also launched in the country.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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In other developments, Bavarian Nordic announces the launch of a clinical trial of its vaccine in younger children, and the WHO adds 2 more tests through emergency listing.
The emergence of the B.1 in 2022 caused the global mpox outbreak, resulting in its detection in 116 countries/territories.
San Diego County officials said an area around 60 homes in Vista will be treated.
Officials said most patients are children ages 15 and younger and that low measles vaccine coverage and malnutrition may be contributing factors.
The case-patient recently traveled abroad, but few other details were given by the institute.
Safety and immunogenicity profiles were similar to those seen in adult studies.
Health officials in the DRC are making progress with administering vaccine to high-risk people, as Nigeria expect to start its campaign next week.
A substantial proportion of mpox infections were clinically undiagnosed.
The detections push the number of African countries reporting mpox cases to 17.
Because not all viruses from mpox cases are sequenced, the findings likely underestimate the prevalence of the newly identified drug-resistant variant.
