Because not all viruses from mpox cases are sequenced, the findings likely underestimate the prevalence of the newly identified drug-resistant variant.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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The report contains temporary recommendations, such as regulatory consideration of mpox vaccine approval and planning for vaccine campaigns.
The ECDC said the risk is high for those who have close contact with affected communities and moderate for people who are contacts of imported clade 1 cases.
The patient sought medical attention in Stockholm but had recently visited Africa.
Twelve percent of animal swabs and 25% of environmental samples from 4 households tested positive for mpox DNA, but blood samples showed no viable mpox or orthopoxvirus antibodies that would indicate previous infection.
As plans move forward to mobilize vaccine, health officials still better epi information to best target the supplies.
Supporting factors included a high disease burden, accelerating spread, a concerning death rate, lack of diagnostics and vaccines, and a need for better coordination among countries.
The group meets on August 14 to assess the emerging complex situation in the African region.
Only 5% of Americans are worried about contracting mpox in the next 3 months.
The European region has so far reported 19 imported Oropouche virus infections, and the virus has recently been linked to severe fetal outcomes.
Though the risk remains very low, the CDC and state partners continue to look for the clade, including in wastewater samples.
