Many of the problems in the mpox response were due to a deflated and exhausted public health workforce across the country.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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People with both mpox and HIV accounted for 40.7% of all mpox cases in California during the study period and 56% of mpox-associated hospitalizations.
While breakthrough infections were mostly mild, infection- and vaccine-induced immunity don't fully protect against mpox.
Roughly 30% of patients reported no male-to-male sexual contact in the 3 weeks before symptom onset or were missing exposure information.
The WHO guidance replaces temporary recommendations, Florida has 15 dengue cases now, and Connecticut confirms 4 people infected with the tick-borne Powassan virus.
One study found hospitalization was lower among older adults who received the vaccine, while another found significant racial and socioeconomic disparities in vaccine uptake.
Pakistan has its second wild poliovirus type 1 case of the year, 4 countries report rising mpox, and the WHO has new resources.
Bavarian Nordic has received a US government contract for $120 million to manufacture more of its Jynneos smallpox/mpox vaccine.
Meanwhile, new clinical findings from Tokyo suggest that asymptomatic mpox cases are underestimated.
The rate of series completion of two doses was similar for intradermal or subcutaneous administration, at 60.2% and 58.8%, respectively.
The WHO reports 316 new mpox cases and 2 new deaths, and the UK warns about a rise in measles transmission.