Researchers say antibiotic trials in children diagnosed as having community-acquired pneumonia likely include many children without radiographic pneumonia.
Investigators say the strategy is readily applicable in low- and middle-income countries, where high rates of ventilator-associated pneumonia drive antibiotic use.
The goal of the intervention was to reduce diagnostic error for ventilator-associated pneumonia.
If approved, V116 would be the first pneumococcal conjugate vaccine specifically designed for adults.
Hospital-acquired pneumonia, is the most common nosocomial infection—and the deadliest.
In the COVID-19 pandemic years 2020 to 2021, IPD incidence dipped to a low of 1.6 per 100,000 children.
The level is slightly higher in school-age kids, but similar to the prepandemic period.
Before COVID, Denmark experienced Mycoplasma outbreaks every 3 to 7 years.
Chinese officials told the WHO that the increase in respiratory illness in children is linked to increased circulation of Mycoplasma pneumoniae and an uptick in flu, RSV, and adenovirus.
Media reports describe overwhelmed children's hospitals in multiple locations in China.
