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Specialist-led intervention program linked to better management of C diff patients

Researchers say the findings suggest oversight of C diff patients by infectious disease specialists may result in better outcomes and resource management.

Chris Dall

Stewardship intervention linked to reduced antibiotic use in pediatric long-term care

The intervention at a pediatric long-term care facility was associated with sustained reductions in ciprofloxacin and other antibiotic use without increasing negative outcomes.

Chris Dall

Preoperative Staph aureus colonization linked to increased risk of postoperative infections

The study authors say the findings highlight the need for S aureus decolonization strategies.

Chris Dall

UK group to fund multidisciplinary research into antimicrobial resistance

UK Research and Innovation this week announced it has dedicated £4.8 million ($6.2 million US) to eight networks working on different aspects of AMR.

Chris Dall

Researchers to study delayed antibiotic strategy for kids with mild pneumonia

The study will investigate whether a strategy known as safety-net antibiotic prescription reduces antibiotic use without worsening clinical outcomes.

Chris Dall

NY officials tell providers to stop using ciprofloxacin to prevent bacterial meningitis

The advisory from the New York State Department of Health was prompted by a rise in ciprofloxacin-resistant strains of Neisseria meningitidis.

Chris Dall

UK health officials warn of rise in ceftriaxone-resistant gonorrhea

Most of the infections have been acquired abroad, and transmission in England has been limited, but officials are worried about the potential for wider spread.

Chris Dall

News Scan for Aug 15, 2017

Latest Saudi MERS case has camel connection

The Saudi Arabian Ministry of Health (MOH) reported a new case of MERS-CoV today in a man from Medina.

The 67-year-old expatriate is in stable condition after presenting with symptoms of MERS-CoV (Middle East respiratory syndrome coronavirus). The man had indirect contact with camels. Indirect contact with camels, including drinking camel milk, is a known risk factor for the disease.

News Scan for Oct 13, 2020

$100 million next-generation genomics initiative begins in Africa

A group led by the African Commission through the Africa Centres for Disease Control and Prevention (Africa CDC), yesterday launched the Africa Pathogen Genomics Initiative (Africa PGI), a $100 million, 4-year partnership to expand and integrate next-generation genomic sequencing (NGS) capabilities across the continent to improve health surveillance and lab networks and better tackle antimicrobial resistance (AMR).

High rate of carbapenem resistance in bacteria that cause newborn sepsis in Africa

A review and meta-analysis found that the pooled prevalence of carbapenem resistance in bacteria from newborns with suspected sepsis in Africa was 30.4%.

Chris Dall

Study: Liquid amoxicillin shortage resulted in more broad-spectrum antibiotic use in US kids

Researchers say the findings raise concerns about antibiotic resistance from inappropriate use of broad-spectrum antibiotics. 

Chris Dall

Study supports ceftolozane-tazobactam over ceftazidime-avibactam for multidrug-resistant Pseudomonas

Differences were driven by improved response rates for patients with pneumonia who were treated with ceftolozane–tazobactam.

Chris Dall

Low-intensity intervention linked to improved outpatient antibiotic prescribing

At six Veterans Affairs clinics, quarterly antibiotic use reports and adverse event letters were associated with lower antibiotic prescribing.

Chris Dall

Report describes rare US vancomycin-resistant Staph case

The case was identified in a nursing home patient in North Carolina, but no transmission was detected.

Chris Dall

Study ties early phenotype-desirable antibiotics to better outcomes for bloodstream infections

In patients with Enterobacterales BSIs, early phenotype-desirable antimicrobial therapy was associated with better 30-day outcomes than delayed therapy.

Chris Dall

Study: Adding macrolides for severe pneumonia not linked to improved outcomes

In more than 8,000 UK pneumonia patients, researchers found no evidence adjunctive macrolides lowered 30-day mortality or shortened time to hospital discharge.

Chris Dall

FDA fast-tracks Staph aureus vaccine

The multivalent toxoid vaccine candidate from LimmaTech Biologics AG is designed to prevent skin and soft-tissue infections caused by Staphylococcus aureus.

Chris Dall

Study: Longer outpatient antibiotic courses not linked to greater risk of harm

Among community-dwelling older adults in Ontario, longer outpatient antibiotic courses were not associated with a greater risk of harm or than shorter courses.

Chris Dall

Global data show rising resistance in Helicobacter pylori infections in kids

A review and meta-analysis of data from 28 countries found significant increases in resistance to clarithromycin, metronidazole, and amoxicillin from 2020 to 2023.

Chris Dall

New guidelines expand recommendations for shorter, all-oral TB treatments

The guidelines recommend a 4-month drug regimen for adults and children with drug-susceptible TB, and a 6-month regimen for those with drug-resistant TB.

Chris Dall

UK study finds penicillin allergy labels are common

Researchers also find that patients with penicillin allergy labels are more likely to get broad-spectrum antibiotics and have a higher risk of resistant infections and adverse events. 

Chris Dall

CARB-X funds development of anti-biofilm vaccine

Clarametyx Biosciences will receive $2.6 million from CARB-X to develop CMTX-301, a vaccine designed to prevent bacterial biofilm formation.

Chris Dall

Stewardship intervention tied to cuts in unneeded antibiotics for bronchitis, viral respiratory infections

Analysis of the intervention, implemented at 49 urgent care clinics, found the biggest reductions among clinicians who were actively engaged.

Chris Dall

Peptilogics receives $3.3 million from CARB-X to develop treatment for fracture-related infections

The funding will help the company develop a slow-release version of zaloganan, an investigational broad-spectrum anti-bacterial and anti-biofilm peptide.

Chris Dall

High prevalence of multidrug-resistant Salmonella, Shigella found in Ethiopian kids

A review and meta-analysis finds that an estimated 1 in 10 children in Ethiopia are infected with Salmonella or Shigella at any given time.

Chris Dall

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