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A report published yesterday in Clinical Infectious Diseases describes a new SARS-CoV-2 mutation that confers resistance to the COVID-19 antiviral drug remdesivir in two persistently infected kidney transplant recipients treated with immunosuppressive drugs.
Illnesses have been reported in 2 more locations.
Three doses of an mRNA vaccine were tied to a 59% lower odds of hospital care than 2 doses.
According to a new non-peer reviewed study out of Israel, the Jynneos vaccine is 79% effective against monkeypox infection.
The study was based on patients eligible for monkeypox vaccine seen in the Clalit Health Services system between Jul 31 and Sep 12, 2022. Of 1,970 subjects eligible for the study, 873 (44%) were vaccinated with Jynneos and completed at least 25 days of follow-up.
A new study based on COVID-19 patients in France shows high reinfection rates among people with different Omicron subvariants, including BA.1, BA.2, and BA.5. The study is published as a research letter in Emerging Infectious Diseases.
"We may see a substantial increase in this disease in the coming months to years."
US experts are closely watching the developments to see how the next months might unfold.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
The risk of a range of neurologic conditions rose significantly in the year after COVID-19 infection among a group of US veterans—regardless of whether they had required hospitalization, according to a study published yesterday in Nature Medicine.
Swiss biopharmaceutical company Ferring Pharmaceuticals announced yesterday that the Food and Drug Administration's (FDA's) Vaccine and Related Biologic Products Advisory Committee (VRBPAC) voted in favor of the company's investigational fecal microbiota transplant (FMT)-based therapy.
Steady drops in new cases continue in North America and Europe, resulting in a 22% overall decline.
One study reveals signs of autoimmune disease in 41% of blood samples 1 year after recovery.
MRI reveals lung damage in children who either had COVID-19 up to a year earlier or have long COVID.
A studye suggests human, animal, and environmental exposures may all play a role.
The WHO says the outbreak location and its mobile population pose a risk of further spread.
Biopharmaceutical company Spero Therapeutics announced today that it has entered into a licensing agreement with GSK for the antibiotic tebipenem pivoxil hydrobromide (HBr).
A study in The Lancet Infectious Diseases demonstrates that previous Omicron BA.1 infection was the most protective factor against BA.2 infection (associated with a risk reduction of 72%) and gave greater protection than primary infection with pre-Omicron SARS-CoV-2 (38%) or three doses of an mRNA vaccine in people with no previous infection (46%).
"We are only beginning to understand the toll of the pandemic on HCW well-being."
After a 5-week drop, global COVID-19 cases stabilized last week, though deaths continued to decline, the WHO says.
A new report from Scotland's national health service shows that three key healthcare-associated infections remained stable or declined from 2020 to 2021.