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Pharmaceutical company Merck announced today that the Food and Drug Administration (FDA) has approved a supplemental New Drug Application for the antibacterial combination drug Recarbrio to treat adult patients with hospital-acquired and ventilator-associated bacterial pneumonia (HABP/VABP) caused by gram-negative pathogens.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
Though no effect was found, the study was stopped early because of low enrollment.
The drug did not show effectiveness for postexposure prevention of COVID-19.
Hot spots include Brazil, Mexico, Peru, India, and Iran, and global deaths are nearing 400,000.
The company that obtained and analyzed study data would not comply with an audit, the study authors say.
The NIH director says some candidates will be ready for large-scale testing as early as July.
A study published today in JAMA Surgery has found a 0.93% overall incidence of COVID-19 among pediatric patients undergoing urgent surgery in three US hospitals, but with wide regional variations.
The World Health Organization (WHO) this week published a technical brief on water, sanitation, hygiene (WASH), and wastewater management to prevent infections and curb the spread of antimicrobial resistance (AMR).
Americans could be at risk of worse outcomes for non-COVID emergencies.
The WHO is worried about accelerating epidemics, especially in Central and South America.
Lancet editors issue a statement acknowledging the criticism of a recent study.
One study found that obese patients were likely to require mechanical ventilation.
The proportion of unnecessary antibiotic prescriptions issued by US physicians' offices and emergency departments (EDs) decreased minimally from 2010 through 2015, driven mainly by a decrease in unnecessary prescriptions for children, researchers reported yesterday in Clinical Infectious Diseases.
Physical distancing, enhanced screening, and quarantining of people with confirmed or suspected COVID-19—without a lockdown—reduced the spread of the novel coronavirus outside of a hard-hit South Korean province by up to 34%, results of a study published yesterday in Emerging Infectious Diseases suggest.
The effects of continued distance learning will likely be worse among students already at risk, the authors say.
Deaths have topped 40,000 in US nursing homes or long-term care facilities, a new analysis suggests.
The index patient is a 27-year-old woman who died in a Wangata hospital on May 18, and a teen girl also died.
About 250,000 of 732,000 recent global cases were in Latin America.
First-year medical residents in Shanghai—500 miles away from the Chinese COVID-19 epicenter of Wuhan—had a steep decline in mood, increased depression and anxiety, and twice the level of fear of workplace violence in the first month of the pandemic, according to a research letter published yesterday in JAMA Network Open.
