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CARB-X announced today funding of up to $4.98 million for BioVersys's new small-molecule drugs targeting Staphylococcus aureus bacteria, including methicillin-resistant S aureus. The drugs could be used as a stand-alone to treat uncomplicated skin and skin-structure infections, as well as in combination with other antibiotics for more severe infections.
Four new cases raise the outbreak total to 3,264 infections, and 3 new deaths bring the fatality toll to 2,181.
Saudi Arabia reported a MERS-CoV infection in a child, which is relatively rare, according to an Oct 26 report from the country's Ministry of Health (MOH).
Nonprofit drug developer TB Alliance announced today that it will partner with an Indian company to manufacture and commercialize pretomanid for treating extensively drug-resistant tuberculosis (XDR-TB).
As cases reach 3,260, the US remains the top donor, but the future of Ebola funding remains unclear.
In its weekly flu update today, the US Centers for Disease Control and Prevention (CDC) reported the first pediatric flu deaths of the new season and noted that the nation's flu activity increased slightly last week but is still at low levels.
New guidelines from the American Dental Association (ADA) recommend against using antibiotics for toothaches in most cases.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
Two of the three wild poliovirus strains are now eradicated globally.
Cases involving travel make it difficult for responders to investigate quickly.
In one key category, under 7% of countries scored in the highest tier.
Officials in North Dakota confirmed chronic wasting disease (CWD) in two mule deer hunted in McKenzie County in the Badlands and in Divide County on the Canadian border. The former represents the first documented CWD case in the Badlands, while the disease was first detected in Divide County last fall.
A new study in Infection Control and Hospital Epidemiology describes several cases of colistin-resistant Klebsiella pneumoniae infections at a hospital in northern India.
Most bloodstream infections caused by resistant E coli involve human-associated strains.
A new study conducted in a 400-bed community hospital in Toronto shows that high-intensity prospective audit and feedback (PAF) was tied to a greater reduction in antimicrobial use than low-intensity interventions. The study appeared yesterday in Infection Control & Hospital Epidemiology.
According to the World Health Organization's (WHO's) Ebola dashboard today, officials in the Democratic Republic of the Congo (DRC) confirmed 2 new cases of Ebola in a 14-month-long outbreak in that country, raising the total to 3,250 infections.
As reported yesterday, 117 of the cases are considered probable infections. The DRC's Ebola technical committee (CMRE) has not yet posted information on the four new cases described yesterday.
Also, a study shows that conflict during the outbreak dampened the effectiveness of vaccine efforts.
The study also found that MRSA infections declined in all facilities, perhaps due to other prevention steps.
The US Centers for Disease Control and Prevention (CDC) announced the launch of a new study to detect and better understand acute febrile illnesses (AFIs) in Belize, Guatemala, and the Dominican Republic.
The World Health Organization (WHO) yesterday published a roadmap for implementing antimicrobial stewardship programs in healthcare facilities in low- and middle-income countries (LMICs).
