Study inconclusive on bias as factor in low flu-vaccine uptake in minorities
A new survey study hints that perceived discrimination may be a factor in low influenza vaccine uptake in racial and ethnic minorities, but the researchers found that it was not significant in comparison with other factors, such as education, according to a report in Medical Care.
Trying to find out why minorities are less likely to get flu shots, the researchers analyzed survey responses from 8,127 white, black, and Hispanic Americans with chronic diseases. The survey was part of an independent evaluation of a national healthcare quality improvement project sponsored by the Robert Wood Johnson Foundation, according to a press release from Wolters Kluwer Health, which publishes Medicare Care.
About 7% of the respondents reported feeling that they were victims of healthcare discrimination at some time in their lives. Of those who perceived discrimination, 32% said they had received a flu vaccine, versus 60% of those who did not perceive discrimination.
The authors said that perceived discrimination, examined alone, accounted for 16% of the racial/ethnic disparity in receipt of the flu vaccine, according to the release. But when they adjusted for other factors that affect flu vaccine uptake, the contribution of perceived bias dropped to 6% and was no longer significant, the report says.
That finding may reflect the relatively low prevalence of perceived discrimination in the nationwide survey, and larger studies might show a significant effect, according to the release.
Three factors were found to be linked with a higher probability of vaccination: having a college degree, nonsmoking status, and trusting the information provided by one's doctor.
"The causes of persistent racial/ethnic disparities are complex and a single explanation is unlikely to be sufficient," the researchers wrote.
June 2016 Medical Care report
May 24 Wolters Kluwer Health press release
Study finds differences in isolated H7N9 cases vs clusters
A study yesterday of 72 isolated H7N9 avian flu cases, 17 family clusters, and 8 clusters tied to live-bird markets in China found that case-fatality rates (CFRs) did not differ among the groups, but sporadic cases tended to involve younger patients with fewer underlying medical conditions.
Researchers from China, Taiwan, and Egypt noted in the International Journal of Infectious Diseases that the family clusters involved human-to-human transmission, whereas the live-market clusters involved co-exposure to the poultry environment. They analyzed primary versus secondary cases for both types of clusters.
The CFRs did not differ statistically among the groups: 36% for sporadic cases, 26% for the family clusters, and 29% for the live-market clusters. The groups differed, however, by average age (36 vs 60 vs 58 years, respectively), co-morbidities (31%, 60%, 54%), avian exposure (72%, 100%, 83%), and H7N9-positive rate (20%, 64%, 35%).
The investigators found no statistical differences between primary and secondary cases in the live-market clusters. In the family clusters, however, incidence of mild cases (6% vs 32%), history of visits to a live-bird market (100% vs 59%), exposure to both birds and infected humans (12% vs 55%), and median days from onset to antiviral treatment (6 vs 3 days) differed significantly from the index to the secondary cases.
The authors attributed the difference in disease severity in the family clusters to older age and greater underlying disease in the primary case-patients.
May 24 Int J Infect Dis study