At 29 days, the estimated cumulative rate of clinical resolution was 83% in tecovirimat recipients and 84% in those given placebo.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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South Africa is experiencing its first spike in clade 2 mpox detections since 2022, and outbreak findings suggest ongoing community spread.
If the country can tap vaccine donations, the tool could help the country battle its surge in novel clade 1 cases.
South Africa has identified 6 new mpox cases in an outbreak that began in late May.
Thirty-nine percent of all California mpox cases occurred in Los Angeles County.
Illnesses have now been reported in 23 of the country's 26 provinces, with the virus causing the heaviest burden in children.
Though data reflect ongoing low-level transmission in multiple regions, the WHO said reduced reporting may underestimate illness levels.
Children have accounted for the major portion of cases and deaths in an ongoing mpox outbreak in the DR Congo.
The effectiveness of preventive vaccination was estimated at 68.2%.
From October 1, 2023, through April 30, 2024, the United States has averaged 59 cases of mpox each week, mostly among unvaccinated people.
The country noted an uptick in clade 1 cases in 2023 and 2024, with 19,919 suspected cases reported.
