At eight months of follow-up, Jynneos recipients not vaccinated against smallpox had lower binding antibody concentrations than those with infection.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
Receive the latest infectious disease information.
"As we implement the interventions that we have, simultaneously, we still pursue some unanswered questions."
CDC Director Walensky says patients and clinicians likely did not recognize this new infection early on.
Two men in their 30s developed encephalomyelitis, or inflammation of the brain and spinal cord.
Bavarian Nordic researchers show that 1- and 2-dose subcutaneous Jynneos vaccinations induce durable neutralizing antibody responses.
MSM should be advised that certain sexual practices and lifestyles put them at very high risk.
Another study reveals that some monkeypox patients develop significant neurological problems, including encephalitis, seizures, and confusion.
"So one of the questions right now is if vaccination will be the optimal tool to curb the outbreak."
New research from Europe also provides more evidence for a sexual transmission route.
Also, a new study shows that, in two thirds of proctitis patients, there was no typical rash on presentation.
A new study from Germany shows no major differences in the clinical picture in those with or without HIV who contract monkeypox. The study, in HIV Medicine, was based on 546 monkeypox cases in Germany, which has one of the highest monkeypox case counts in Europe. The study is published in HIV Medicine.
