At 29 days, the estimated cumulative rate of clinical resolution was 83% in tecovirimat recipients and 84% in those given placebo.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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Director-General Tedros Adhanom Ghebreyesus, PhD, of the World Health Organization (WHO) today said many European countries, including Germany and the Netherlands, were showing continued slowing of new monkeypox cases, while countries in the Americas (save for Canada) are still seeing increased case counts.
The patient who died was described as being severely immune-compromised.
The funds will support the first US-based fill-and-finish effort of Bavarian Nordic's Jynneos vaccine.
Half of men who have MSM are changing their sexual behaviors because of the monkeypox outbreak.
"Insufficient awareness of public health measures are combining with a lack of access to vaccines."
Beginning today, those getting a monkeypox vaccine in New York City will receive an intradermal injection of the Jynneos vaccine as part of a dose-sparing strategy. The city immediately opened 12,000 vaccine slots upon announcing the decision yesterday.
In other US news, North Carolina reported a pediatric monkeypox case.
In addition, Brazil has confirmed 77 cases of the poxvirus in children.
California health officials are confronting growing numbers of monkeypox cases, with numbers doubling in Los Angeles County over the past 2 weeks.
Multiple surface sites tested positive for virus DNA in the home of 2 patients.
In the US, officials are making more vaccine doses available.
