Investigators say switching to oral antibiotic therapy in patients with low risk of complications could simplify treatment and allow for earlier discharge.
Reduced antibiotic consumption was related to de-escalation and discontinuation of empiric antibiotic therapy during the intervention period.
Investigators say the strategy is readily applicable in low- and middle-income countries, where high rates of ventilator-associated pneumonia drive antibiotic use.
Lack of human resources, absence of leadership, and limited microbiology laboratory support are some of the issues cited.
The CRISPR-engineered bacteriophage therapy from Locus Biosciences targets urinary tract infections caused by drug-resistant E coli.
The two groups will combine efforts to genetically track threats ranging from mosquito borne pathogens to pandemic flu.
In a population-based study, patients recently exposed to antibiotics and proton pump inhibitors had an 18-fold increase in the risk of C diff infection.
In the intention-to-treat population, the vaccine effectiveness of the typhoid vaccine was 78%.
High use of Watch antibiotics was reported among patients in Ivory Coast, Burkina Faso, Democratic Republic of the Congo, and South Africa.
The UK's Medicines and Healthcare products Registry says fluoroquinolones should be used only when no other appropriate antibiotics are available.
The findings highlight the need to boost infection prevention and control and antimicrobial stewardship efforts in Greek hospitals.
Among the exposures the study will evaluate is antibiotic use, which has been shown to disrupt the microbiome.
An investigation of the clinic identified gaps in environmental cleaning practices, surgical device disinfection.
The trial found that the anti-staphylococcal lycin exebacase plus standard-of-care antibiotics failed to improve clinical response compared with antibiotics alone.
Four colonization cases have been reported in patients with links to the same long-term acute-care hospital.
Researchers say antibiotic trials in children diagnosed as having community-acquired pneumonia likely include many children without radiographic pneumonia.
Treatment with the narrow-spectrum investigational antibiotic ridinilazole resulted in a 53% relative reduction of recurrent C difficile infection compared with vancomycin.
A review of randomized controlled trials found that Asian and Black participants were underrepresented.
A brand of artificial tears manufactured in India was confirmed as the source of the multi-state outbreak.
The results of a phase 3 trial suggest cefepime-taniborbactam is a treatment option for patients with complicated UTIs caused by difficult-to-treat, gram-negative bacteria.
Researcher says ongoing surveillance is needed to ensure that women receive optimal empiric antibiotics for uncomplicated UTIs.
Researchers say the findings highlight the need for updated testing and treatment guidelines for the sexually transmitted bacteria.
The study also found "severely high" levels of resistance to first-line treatments for UTIs in Tanzania, Kenya, and Uganda.
The Minimized Risk of Antimicrobial Resistance certification is given to manufacturing sites that have demonstrated a commitment to controlling antibiotic discharge.
More than half of the antibiotics prescribed by VA dentists in 2019 do not have guidelines supporting their use.
