A review and meta-analysis of studies in Pakistan, India, and Zimbabwe finds vaccine effectiveness was 87% in preventing culture-confirmed typhoid in children.
Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.
A review and meta-analysis finds Salmonella Typhi and Paratyphi samples from human infections in Pakistan were highly resistant to first-line and other commonly used antibiotics.
Researchers say the introduction of typhoid conjugate vaccines in these countries could help protect communities, especially school-aged children.
In the intention-to-treat population, the vaccine effectiveness of the typhoid vaccine was 78%.
Montana's H1N2v case was reported in a patient who had attended an agricultural fair.
Genomic analysis of extensively drug-resistant typhoid isolates in Pakistan reveals numerous circulating XDR variants.
Typhoid fever has become increasingly resistant to antibiotics over the past 50 years.
A phase 3 clinical trial conducted in Malawi has found that a single dose of typhoid conjugate vaccine (TCV) is safe and more than 80% effective at protecting children against typhoid fever, an international team of researchers reported yesterday in the New England Journal of Medicine.
The agency confirms 9 cases not tied to international travel but says reporting for 2020 is not yet complete.
