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Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
A study of 4,737 COVID-19 patients in Israel conducted during the Omicron surge concludes that Pfizer's antiviral drug Paxlovid roughly halves the risk of severe COVID-19 or death, according to findings published yesterday in Clinical Infectious Diseases.
Moms' vaccination provided infants 71% protection against Delta and 33% against Omicron.
Also, a study notes potential undetected spread of the disease in Europe at least since early April.
Pfizer and BioNTech submitted an EUA request for their vaccine in kids 6 months to 4 years old.
An analysis of studies published over the past two decades shows that human intestinal carriage of multidrug-resistant (MDR) Escherichia coli has risen substantially in healthcare and community settings around the world, researchers reported today in JAC-Antimicrobial Resistance.
Compared with reverse-transcription polymerase chain reaction (RT-PCR) testing, dogs can detect COVID-19 infections via scent with high sensitivity (97%)—though lower specificity (91%)—even when patients are asymptomatic, according to a study in PLOS One yesterday.
Though falling or holding steady elsewhere, COVID cases are still increasing in the Americas region.
"There may have been undetected transmission for a while," a WHO official says.
Too-high pulse oximetry readings led clinicians to believe patients weren't ill enough for certain therapies.
A new analysis of a randomized clinical trial shows that a repeated post-discharge decolonization regimen for methicillin-resistant Staphylococcus aureus (MRSA) carriers reduced MRSA colonization overall and at multiple body sites, researchers reported yesterday in Clinical Infectious Diseases.
Three COVID-19 vaccine doses offer good protection against infection and hospitalization, including those caused by variants of concern—regardless of brand, type, or combination, according to an ongoing meta-analysis published yesterday in BMJ.
The findings reveal substantial global collateral damage during the pandemic.
In the US, the more transmissible BA.2.12.1 subvariant now makes up nearly 60% of sequenced samples.
"There's a window of opportunity where this can be contained," a WHO official says.
About 75% of COVID-19 deaths in the least-vaccinated Chicago areas could have been prevented if their uptake would have equaled that of the highest-coverage areas during the Alpha and Delta variant surges, suggests a study late last week in JAMA Network Open.
The World Health Assembly (WHA) last week passed a resolution that aims to make infection prevention and control (IPC) a critical element of addressing healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) and of preparing for infectious disease health emergencies.
Long COVID can affect even fully vaccinated people after mild breakthrough infections.
Report characterizes risks in the 100-day supply chains of 143 essential prescription drugs.
International survey finds 62% reported 1 or more symptoms of burnout, and 31% reported 2.