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Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
The National Institutes of Health this week announced a $2.4 million grant for a clinical trial to study responsible use of antibiotics in the treatment of severe gum disease.
The sensitivity of home rapid antigen COVID-19 tests peaks 4 days after symptom onset, suggesting that a negative antigen test should be followed by a second test in 1 or 2 days, according to a prospective study published today in JAMA Internal Medicine.
Cases are rising in South Africa, where researchers are closely tracking two new Omicron subvariants, BA.4 and BA.5. Both seem to be more transmissible than BA.2.
Risk factors for severe COVID varied by age, with BMI and underlying conditions more notable for younger adult patients and lab results more predictive for older people.
Earlier studies in animals and adults suggested a link between antibiotic use and vaccine response, and these are the first findings in children.
The Wisconsin Department of Health Services (WDHS) in an alert to clinicians said it is investigating at least four unexplained hepatitis cases in children, including one who needed a liver transplant and one who died. Also, California officials said today that they are investigating seven cases
Using excess mortality data collected by the Centers for Disease Control and Prevention (CDC), researchers from Georgetown University found significant regional differences in mortality rates due to COVID-19, with a disproportionate number of virus deaths in Southern states.
Researchers detail new findings on long COVID risk, plus a promising role for occupational therapy to help cope with symptoms.
With deaths at the lowest point in about 2 years and cases declining, the WHO urged countries to keep a close eye on cases and virus changes.
Research suggests exposure to fungicides is promoting resistance in Aspergillus fumigatis.
Following the reappearance of Ebola in the Democratic Republic of the Congo's (DRC's) Equateur province, the country today launched an rVSV-EBOV vaccine campaign, tapping an initial shipment of 200 doses, the World Health Organization (WHO) African regional office said today.
Two thirds of family members restricted from visiting loved ones in the ICU had symptoms of PTSD 3 months later.
Sepsis remains a leading cause of death in young children, with 20 million global cases and 2.9 million deaths.
The roadmap "will provide a framework for the development of broadly protective coronavirus vaccines to ensure that we are prepared to respond" to future SARS-CoV-2 variants or other viruses with pandemic potential.
Also, federal officials are taking steps to make sure Pfizer's COVID-19 pill, Paxlovid, will be widely available across the US.
The Democratic Republic of the Congo (DRC) has confirmed a second case in its latest Ebola outbreak in Equateur province, a close contact of the index patient. The newest patient has also died from her infection.
Israelis aged 60 and older given a fourth dose of the Pfizer/BioNTech COVID-19 vaccine amid the Omicron surge had a 64% lower risk of hospitalization and 78% lower risk of death than those who received three doses, suggests an observational study published yesterday in Nature Medicine.
Data show a 36% to 68% lower risk of a COVID-19 hospital stay with Omicron.
The virus has claimed the life of a 31-year-old man in Equateur province.
US cases, now nearing 50,000 per day, are rising fastest in the Midwest and Northeast.
